Erhöhter klinischer und wirtschaftlicher Nutzen durch PROSIT (Proteinurie Screening und Intervention) bei Typ 2 diabetischen Patienten

Gozzoli, Valerio; Palmer, AC; Brandt, A.; Weiss, C; Piehlmeier, W.; Landgraf, R.; Renner, R

doi:10.1055/s-2000-7670

Cited by 15 publications

(1 citation statement)

References 8 publications

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“…Darüber hinaus legen gesundheitsökonomische Analysen den Schluss nahe, dass wesentliche Kosten der Diabetesbehandlung durch diabetische Komplikationen entstehen und dass eine effektive Prävention solcher Komplikationen auch ökonomisch sinnvoll ist (7,12,14,16,17,28,33).…”

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Wie häufig sind Diabetes-bedingte Amputationen unterer Extremitäten in Deutschland?

Heller

Günster

Schellschmidt

2004

Dtsch med Wochenschr

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Wie häufig sind Diabetes-bedingte Amputationen unterer Extremitäten in Deutschland?

Heller

Günster

Schellschmidt

2004

Dtsch med Wochenschr

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Risk and potential risk reduction in diabetes type 2 patients in Germany

Häussler

Berger

Mast³

et al. 2005

Eur J Health Econ

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Avoiding serious complications such as stroke, myocardial infarction, and amputations in diabetes patients is the main interest of long-term treatment. Given the considerable prevalence of diabetes type 2 in industrialized countries this is a major public health concern as well as a burden to health care systems. The present study estimated the current risk of major complications occurring in the German diabetes type 2 population and explored the potential for further risk reduction. Risk reduction can be achieved when physiological and behavioral parameters (HbAlc, blood pressure, cholesterol level, body mass index, smoking) are set to target values recommended in guidelines. To estimate individual risk and potential risk reduction the multifactor disease model Mellibase was employed. Data were obtained from the German Health Survey of 1998, which includes a sample of 7,124 individuals representative of the German population. The survey shows a prevalence rate of 6.3% for diabetes type 2 in persons older than 35 years. The analyses reveal that the overall potential for risk reduction is moderate (e.g., the average reduction potential of the 10-year risk of stroke is 5.7%). A majority of parameter ranges found in the patient population are either already close to the recommended values (HbA1c), are not alarmingly higher than in the general population (blood pressure) or have little impact on risk reduction. In addition nonmodifiable risk factors such as duration of the illness and advanced age constrain possible improvements. However, there is a wide variation in the actual risk between individuals (e.g., the 10-year risk of stroke varies between 2.2% and 79.8%), and thus a wide variation in potential risk reduction (the risk reduction potential for stroke varies between 0% and 53.4%). Intensified treatment should therefore (a) focus on relevant subgroups of patients taking their risk reduction potential into account and (b) aim at improvement in the overall metabolic profile rather than concentrating on single risk factors.

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Telediabetologie

Kempf

Martin

2012

Diabetologe

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Erhöhter klinischer und wirtschaftlicher Nutzen durch PROSIT (Proteinurie Screening und Intervention) bei Typ 2 diabetischen Patienten

Cited by 15 publications

References 8 publications

Wie häufig sind Diabetes-bedingte Amputationen unterer Extremitäten in Deutschland?

Wie häufig sind Diabetes-bedingte Amputationen unterer Extremitäten in Deutschland?

Risk and potential risk reduction in diabetes type 2 patients in Germany

Telediabetologie

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