Ergotamine-induced Colitis

Abstract

We report on a 45-year-old woman with ulcerative colitis of the rectum that arose after the use of up to 6 suppositories of a preparation containing ergotamine daily over a period of 6 years. On the basis of a review of the literature the clinical, endoscopic and histological features of the ergotamine-induced colitis are characterized.

Long-Term Treatment of Patients with Endocrine Gastrointestinal Tumours with the Somatostatin Analogue SMS 201-995

“…6). (19), has been shown to be of therapeutic value in patients with gastrointestinal endocrine tumours such as VIPomas (21,22,30), gastrinomas (23,31), and carcinoid tumours (20). In two VIPomas, tumour regression has been described (21,30).…”

Anorektaler Ergotismus

“…Komplikation ist die lokale Minderdurchblutung der Rektumwand nach rektaler Ergotamingahe (1,2,6,9,10,13,14,15,16).…”

“…Die wichtigste Therapie ist das konsequente Absetzen den engotaminhaltigen Suppositonien. Fruhe Verandenungen bilden sich in den Regel komplett zunUck (15). Kleinene Blutungen sistienen bereits nach Absetzen den Noxe.…”

Solitary Rectal Ulcer Syndrome: Aetiology, Investigation and Management

“…The association of solitary rectal ulcer ation and the use of ergotamine tartrate has been described [12,13], Ergotamine-induced ulcers can be distinguished from the solitary rectal ulcer syndrome by the lack of mucosal prolapse, absence of a history of difficulty in defaecation and rapid healing after stopping the drug. Some of the reported cases have been shown to have fibromuscular oblitera tion of the lamina propria and this is thought to be due to mucosal ischaemia induced by the ergot preparation.…”