Abstract:The reproducibility of embryonic development is a remarkable feat of biological organization, but the underlying mechanisms are poorly understood. Clearly, gene regulatory networks are central to the orderly progression of development, but noisy molecular and cellular processes should reduce reproducibility. Here, we identify ergodicity, a type of dynamical stability, as underlying the reproducibility of development. In ergodic systems, a single timepoint measurement equals a time average. Focusing on the zebr… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.