Erfahrungen mit der Thymektomie als Behandlungsmethode der Myasthenia gravis

Weimann, Stefanie; Gschnitzer, Franz

doi:10.1007/bf02601034

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Acta Chir Austriaca

1976

DOI: 10.1007/bf02601034

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Erfahrungen mit der Thymektomie als Behandlungsmethode der Myasthenia gravis

Stefanie Weimann¹,

Franz Gschnitzer²

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1980

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Plasmapheresis therapy in myasthenia gravis

Dau

1980

Muscle and Nerve

101

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Plasmapheresis in the treatment of myasthenia gravis has led to disparate results when applied by different investigators because of considerable differences in the volume, number, and tempo of plasmaphereses and in the type and amount of concomitant immunosuppressive drug therapy. Used as short-term crisis intervention, plasmapheresis produces temporary clinical improvement and reduction in titer of antibody to acetylcholine receptor, even without accompanying drug therapy. When applied as long-term primary therapy under optimal conditions, plasmapheresis is capable of generating stable improvement in most patients. This response appears to result from a synergistic action with immunosuppressive drugs, since it is characterized by a sustained reduction in titer of antibody to acetylcholine receptor. Where clinical circumstances warrant cytotoxic immunosuppression in patients with myasthenia gravis, consideration should be given to the simultaneous employment of plasmapheresis, in order to maximize benefit to the patient from a given exposure to drug therapy.

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Plasmapheresis therapy in myasthenia gravis

Dau

1980

Muscle and Nerve

101

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Erfahrungen mit der Thymektomie als Behandlungsmethode der Myasthenia gravis

Cited by 1 publication

References 5 publications

Plasmapheresis therapy in myasthenia gravis

Plasmapheresis therapy in myasthenia gravis

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