Erectile impotence in multiple sclerosis: a neurophysiological study

Ghezzi, Angelo; Malvestiti, G.M.; Baldini, S.; Zaffaroni, Mauro; Zibetti, A

doi:10.1007/bf00936883

Cited by 48 publications

(25 citation statements)

References 27 publications

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“…There are controversial findings of studies that investigated the relationship between age and SD in patients with MS which was significant according to some studies (2,4,5,11,20), but to other studies it was not (3,10,21). Although the average age of the patients with SD was higher than that of the patients without SD in our study, the avarage ages in both groups were generally high.…”

Section: R Re Es Su Ul Lt Ts Scontrasting

confidence: 77%

See 1 more Smart Citation

Investigation of Factors Related to Sexual Dysfunction in Patients with Multiple Sclerosis

Edemci¹,

Karakuş²,

Uçan³

et al. 2010

tftr

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S Su um mm ma ar ry y O Ob bj je ec ct ti iv ve e: : Sexual dysfunction (SD) is an important, but generally underestimated symptom in the course of multiple sclerosis (MS). The aim of this study was to investigate the factors related to SD in MS patients. M Ma at te er ri ia al ls s a an nd d M Me et th ho od ds s: : Twenty-one MS patients with and 21 MS patients without SD were included in this study. Age, SD duration, disease duration, marital status, educational status, bladder and bowel dysfunction, disability, independence, cognitive performances and psychological functioning and sexual function scales have also been assessed. R Re es su ul lt ts s: : SD correlated with age (p=0.029), disease duration (p=0.045), bladder dysfunction (X 2 =0.011; p=0.012). Positive correlations were found between disease duration and 5-point sexual function scale in SD patient (rs=0.419; p=0.027). However, SD did not correlated with bowel dysfunction (X 2 =0.469; p=0.418), disability (p=0.190), level of independence (p=0.146) and cognitive performances (p=0.212). The brain stem involvement was higher in patients with SD (X 2 =0.001; p=0.001). C Co on nc cl lu us si io on n: : The prevalence of SD increases with the patient age and prolonged disease duration. SD is related to bladder dysfunction and brain stem involvement. However, increased disability does not affect SD. Turk J Phys Med Rehab 2010;56:130-4. K Ke ey y W Wo or rd ds s: : Multiple sclerosis, sexual dysfunction Ö Öz ze et t A Am ma aç ç: : Seksüel disfonksiyon (SD), multipl skleroz (MS) seyri s›ras›nda görülen ancak genellikle gözard› edilen bir semptomdur. Bu çal›flman›n amac› MS'li hastalarda görülen SD ile iliflkili faktörlerin araflt›r›lmas›d›r. G Ge er re eç ç v ve e Y Yö ön nt te em m: : Çal›flmaya MS'ye ba¤l› SD'si bulunan 21 hasta ve bulunmayan 21 hasta dahil edildi. Yafl, SD süresi, hastal›k süresi, medeni durum, e¤itim durumu, mesane ve barsak disfonksiyonu varl›¤›, disabilite, konginitif performans, psikolojik fonksiyonlar ve seksüel durum de¤erlendirildi. B Bu ul lg gu ul la ar r: : SD varl›¤›; yafl, hastal›k süresi ve mesane disfonksiyonu varl›¤› ile koreleydi (s›ras›yla p=0,029, p=0,045, X 2 =0,011; p=0,012). Hastal›k süresi ve 5 puanl›k seksüel fonksiyon skalas› aras›nda, SD olan hastalarda pozitif korelasyon bulundu (rs=0,419; p=0,027). Buna ra¤men SD varl›¤› ile barsak disfonksiyonu varl›¤› (X 2 =0,469; p=0,418), disabilite düzeyi (p=0,190) ve kognitif performans (p=0,212) düzeyi korele bulunmad›. SD'lu hastalarda beyin sap› tutulumu daha yüksekti (X 2 =0,001; p=0,001). S So on nu uç ç: : SD s›kl›¤› hasta yafl› ve hastal›k süresi art›kça artmaktad›r. SD mesane disfonksiyonu ve beyin sap› tutulumu ile iliflkilidir. Ancak disabilite düzeyinin artmas› SD'nin görülme s›kl›¤›nda art›fla neden olmamaktad›r. Türk Fiz T›p Rehab Derg 2010;56:130-4. A An na ah ht ta ar r K Ke el li im me el le er r: : Multipl skleroz, seksüel disfonksiyon

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Section: R Re Es Su Ul Lt Ts Scontrasting

confidence: 77%

“…Although the sexual dysfunction (SD) is an important problem seen in the course of MS, it is generally undervalued and few studies exist on this subject. SD is rarely a symptom at disease onset (4,5). It may occur at any time during the course of MS and develops in more than half of the patients with MS (6,7).…”

mentioning

confidence: 99%

Investigation of Factors Related to Sexual Dysfunction in Patients with Multiple Sclerosis

Edemci¹,

Karakuş²,

Uçan³

et al. 2010

tftr

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“…This high coincidence of neurophysiological and vascular factors is also true for the subset of patients suffering from MS in whom 4 out of 10 exhibited also pathological duplex sonographic measurements. Due to the small sample of MS patients in our study, however, the question, raised by Ghezzi et al, 29 how important vascular factors for the manifestation of erectile dysfunction in MS patients are, cannot be de®nitely answered.…”

Section: ±55mentioning

confidence: 82%

“…In patients with a history of multiple sclerosis, Ghezzi et al 29 found in a sample of 34 patients 9% pathological BCR-L and 77% pathological pudendal nerve SSEP without any correlation to the respective erectile capacity, whereas Betts et al 30 described in an equivalent sample of 34 MS-patients a considerable even if not as high as for tibial SSEP correlation between pudendal SSEP and hyperre¯exogenic bladder as well as Kurtzke score. Considering erectile function, however, no correlation was observed.…”

Section: ±17mentioning

confidence: 96%

Bulbocavernosus-reflex latencies and pudendal nerve SSEP compared to penile vascular testing in 669 patients with erectile failure and other sexual dysfunction

Fabra¹,

Porst²

1999

Int J Impot Res

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The purpose of this current study was to ®nd out the coincidence of pathological penile vascular supply with pathological data in Bulbocavernosusre¯ex latency (BCR-L) measurements and Pudendal Nerve SSEP (PudSSEP) recordings. Six hundred and sixty-nine males (642 with erectile dysfunction, 27 with different sexual disturbances) (mean age 49.3 y, range 17±76 y) underwent consecutively a battery of neurophysiological investigations together with pharmacotesting of cavernous bodies combined with duplex sonography of penile arteries. Pathological vascular ®ndings were indicated in 286 men (43%), pathological neurophysiological ®ndings in 264 men (39%). Normal ®ndings in both investigations (vascular and neurophysiological) were encountered in 252 men (38%); 131 men (19%) revealed pathological data exclusively in the neurophysiological parameters, 153 (23%) exclusively in the vascular parameters and 133 (20%) in both.The highest percentages of pathological ®ndings were observed in patients with diabetes mellitus (110 out of 131, 88%) and patients who had sustained pelvic trauma or surgery (36 out of 44, 82%), in contrast to the lowest percentage in patients with a proven psychogenic etiology (10 out of 38, 26%). Somewhat surprising was the rather high proportion of vascular impairment in patients with de®ned neurological diseases such as alcohol abuse (20 out of 51, 43%), polyneuropathy (PNP) of various etiology (9 out of 19, 47%), lumbosacral radiculopathies (26 out of 65, 40%), and CNS diseases (24 out of 52, 46%), about half of them coinciding with pathological neurophysiological ®ndings. Even if the validity of BCR-L measurement and PudSSEP recordings in the assessment of neurogenic impotence was controversely discussed, we conclude that in a large number of impotent males both neurogenic and vascular factors are responsible for the onset of erectile dysfunction.

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“…7 The typical manifestation of a sexual dysfunction in MS is loss of libido, sexual arousal, or orgasmic capacity. [8][9][10] We report on a woman with MS who experienced hypersexual feelings and behavior as part of an MS exacerbation.…”

Section: Introductionmentioning

confidence: 99%

Hypersexual sensations and behavior in a multiple sclerosis exacerbation: a case report

2004

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Erectile impotence in multiple sclerosis: a neurophysiological study

Cited by 48 publications

References 27 publications

Investigation of Factors Related to Sexual Dysfunction in Patients with Multiple Sclerosis

Investigation of Factors Related to Sexual Dysfunction in Patients with Multiple Sclerosis

Bulbocavernosus-reflex latencies and pudendal nerve SSEP compared to penile vascular testing in 669 patients with erectile failure and other sexual dysfunction

Hypersexual sensations and behavior in a multiple sclerosis exacerbation: a case report

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