Erectile Impotence in Diabetic Men: Aetiology, Investigation, and Management

Wiles, PhilipG

doi:10.1111/j.1464-5491.1992.tb01726.x

Cited by 13 publications

(2 citation statements)

References 45 publications

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“…Though the debate about the mechanism of ED among diabetic patients is on-going, evidence suggests that it is often related to a complex mechanism involving several factors including arterial impairment, poor glycemic control, neurologic damage, autonomic neuropathy, and hormone imbalance [4] , [8] , [9] , [10] , [11] . Though ED in patients with DM is a highly preventive challenge, it highly threatens the well-being of clients by increased psychological distress [12] , [13] , decreased quality of life [14] , [15] , and increased risk of cardiovascular disease [16] , [17] .…”

Section: Introductionmentioning

confidence: 99%

Risk factors of erectile dysfunction among diabetes patients in Africa: A systematic review and meta-analysis

Shiferaw

Akalu

Petrucka

et al. 2020

Journal of Clinical & Translational Endocrinology

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Background Erectile dysfunction in men is a common underestimated complication of diabetes mellitus, which is becoming a significant public health problem both in developing and developed countries. Erectile dysfunction threatens the well-being of clients, hence determining its risk factors and controlling it at an early stage is vital to preventing serious consequences and the burden of the disease. Therefore, this study aimed to systematically evaluate erectile dysfunction risk factors in patients with diabetes mellitus in Africa. Methods PubMed, Web of Science, Scopus, African Journals Online, Wiley Online Library and Google Scholar were searched and complemented by manual searches. Egger's regression test was used to determine publication bias. The I 2 statistic was used to check heterogeneity between the studies. DerSimonian and Laird random-effects model was applied to estimate pooled effect size, odds ratios, and 95% confidence interval across studies. STATA version 14 statistical software was used for the meta-analysis. Result Overall, 17 studies with 6002 study participants were included to identify risk factors of erectile dysfunction among diabetic patients. Duration of diabetes mellitus >10 years (AOR = 2.63; 95% CI 1.27, 5.43), age >40 years (AOR = 1.24; 95% CI: 1.03, 1.51), peripheral neuropathy (AOR = 2.34; 95% CI: 1.51, 10.72), no physical exercise (AOR = 1.63; 95% CI: 1.49, 1.78), testosterone level <8 nmol/l (AOR = 2.83; 95% CI: 1.06, 12.86), and peripheral vascular disease (AOR = 2.85, 95% CI: 1.54–5.27) were significantly associated with erectile dysfunction among diabetic patients. Conclusions This study found that long duration of diabetes mellitus, age >40 years, testosterone deficiency, peripheral neuropathy, not involved in physical exercise, peripheral vascular disease, were significantly associated with increased risk of erectile dysfunction among diabetic patients Therefore, situation-based interventions and country context-specific preventive strategies should be developed to decrease the risk factors of erectile dysfunction among patients with diabetes mellitus.

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Section: Introductionmentioning

confidence: 99%

Risk factors of erectile dysfunction among diabetes patients in Africa: A systematic review and meta-analysis

Shiferaw

Akalu

Petrucka

et al. 2020

Journal of Clinical & Translational Endocrinology

View full text Add to dashboard Cite

show abstract

“…18 It has been associated with increased age, poor glycemic control, smoking, increased alcohol intake, depression, use of specific types of medications, and microvascular diabetic complications, such as retinopathy and nephropathy. [19][20][21][22][23][24] Impotence can cause great domestic disharmony and may be the basis of many seemingly inexplicable psychiatric and physical symptoms.…”

Section: Erectile Impotencementioning

confidence: 99%