Erectile function after urethral reconstruction

Carlton, Joshua; Patel, Maharshi; Morey, Allen F.

doi:10.1111/j.1745-7262.2008.00349.x

Cited by 20 publications

(18 citation statements)

References 18 publications

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“…It is this parameter that governs which reconstructive procedure should be selected. Carlton et al [7] found that men undergoing repair of longer strictures report erectile dysfunction more often. In our study, when different stricture lengths were compared, patients with 16 cm of strictured urethra had comparatively lower sexual desire (mean SD score of 5.78).…”

Section: Discussionmentioning

confidence: 99%

A Study on Sexual Function of Men with Anterior Urethral Stricture before and after Treatment

Sharma¹,

Kumar²,

Mandal³

et al. 2011

Urol Int

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Introduction: Male urethral reconstruction for anterior urethral stricture has become increasingly popular and effective. Little is known about its potential impact on subsequent sexual performance. Patients and Methods: Thirty-four patients of anterior urethral stricture disease were studied from January 2008 to November 2009. The data were collected before surgery and at a follow-up of 3 months after completing the treatment. Evaluation of sexual function was done using O’Leary’s Brief Male Sexual Function Inventory. Results: Patients were divided into two categories: <40 and >40 years of age. Younger patients had more improvement in ejaculatory function and overall satisfaction after surgery than elderly. Elderly males had lower sexual drive scores. Patients with traumatic stricture had significant improvement in ejaculation and overall satisfaction. Patients without history of prior optical internal urethrotomy or dilatations reported a significant improvement in their ejaculatory function and overall satisfaction. Conclusion: Erectile dysfunction is not significant after anterior urethral reconstruction. The improvement is most pronounced in ejaculation and overall satisfaction, which was mostly appreciated by younger men. A successful urethral reconstructive procedure leads to rehabilitation of the patient back into a healthy sexual life. Dorsomedial dissection of bulbar urethra should be limited and cautery use should be minimized in that area.

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Section: Discussionmentioning

confidence: 99%

A Study on Sexual Function of Men with Anterior Urethral Stricture before and after Treatment

Sharma¹,

Kumar²,

Mandal³

et al. 2011

Urol Int

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“…Treatment of urethral stricture is always a great challenge for urologists, although a paradigm shift in managing this disease has occurred within the past decades. In addition to attaining meaningful improvement in voiding efficiency and alleviating symptoms, satisfaction with remaining erectile function after surgery is also an important criterion of ideal postoperative outcome for urethroplasty .…”

Section: Introductionmentioning

confidence: 99%

The Relationship Between Erectile Dysfunction and Open Urethroplasty: A Systematic Review and Meta-Analysis

Cao

Barbagli

et al. 2013

The Journal of Sexual Medicine

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Introduction Various urethroplasty techniques have been used to treat urethral stricture. Whether the patient erectile function is affected by this open surgery is still controversial. Aim The aim of this study is to determine the relationship between erectile function and open urethroplasty. Methods A systematic review of the literature was performed using Medline, Embase, the Web of Science, and the Cochrane Library databases through October 2012 to identify articles published in any language that examined the effect of open urethroplasty on the risk of erectile dysfunction (ED). This meta-analysis was conducted according to the guidelines for the meta-analysis of observational studies in epidemiology. Main Outcome Measures The incidence of ED after urethroplasty. Results This meta-analysis consisted of 23 cohort studies, which included 1,729 cases. No significant difference was noticed in patients with anterior urethral stricture before or after intervention (odds ratio [OR] = 0.86; 95% confidence interval [CI]: 0.52–1.40; P = 0.53). While statistical difference in the incidence of ED was revealed in patients before and after intervention for a posterior urethral (OR = 2.51; 95% CI: 1.82–3.45; P < 0.001), further comparisons demonstrated that most anterior urethroplasties did not have an obvious effect on patient erectile function. However, it seems that the incidence of ED was higher in the bulbar anastomosis group than in the oral graft urethroplasty group (OR = 0.32 95% CI: 0.11–0.93; P = 0.04). For the posterior urethroplasty, previous operative history did not show a strong relationship with ED. No statistically significant difference in the risk of ED was demonstrated comparing the posterior urethral reconstructive techniques included in this analysis. Conclusion The adverse effect of urethroplasty itself on erectile function is limited, as more patients recover erectile function after urethral reconstruction. For anterior urethroplasty, bulbar anastomosis might cause a slightly higher incidence of ED than other operations. For posterior urethroplasty, trauma might be the main cause of ED.

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“…Tissue engineering is one of the exciting areas in biotechnology. It combines the principles and methods of the life sciences with those of engineering to elucidate fundamental understanding of structure-function relationships of normal and diseased tissue to facilitate the development of materials and methods to repair damaged diseased tissue and create entire tissue replacement [1][2][3]. In our previous study, foreskin epidermal cells successfully replaced urethral epithelium cells in urethra reconstruction [4].…”

Section: Introductionmentioning

confidence: 99%

Long-term study of male rabbit urethral mucosa reconstruction using epidermal cell

Fu¹,

Deng²,

Song³

et al. 2008

Asian Journal of Andrology

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Erectile function after urethral reconstruction

Cited by 20 publications

References 18 publications

A Study on Sexual Function of Men with Anterior Urethral Stricture before and after Treatment

A Study on Sexual Function of Men with Anterior Urethral Stricture before and after Treatment

The Relationship Between Erectile Dysfunction and Open Urethroplasty: A Systematic Review and Meta-Analysis

Long-term study of male rabbit urethral mucosa reconstruction using epidermal cell

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