Erectile Dysfunction in Relation to Metabolic Disorders and the Concentration of Sex Hormones in Aging Men

Abstract

Background: The aim of this study was to analyze the relationship between the prevalence of erectile dysfunction in men as diagnosed by the International Index of Erectile Function (IIEF) questionnaire and the respective levels of sex hormones and biochemical parameters, as well as indices of visceral fat accumulation and activity. Material and Methods: The study comprised 148 male (60–75 years) patients from primary care outpatient clinics in the city of Szczecin (Poland). The men were asked to complete a shortened survey questionnaire with sociodemographic data, as well as a shortened version of the IIEF (five items). Venous blood samples were collected. Total testosterone (TT), estradiol (E2), sex hormone-binding globulin (SHBG), dehydroepiandrosterone sulfate (DHEAS), total cholesterol (ChT), low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides (TG), fasting plasma glucose (FPG) and albumin were determined. Lipid accumulation product (LAP) and visceral adiposity index (VAI) were calculated. Results: A correlation was found in the analysis of LAP index values (OR = 1.017; p = 0.050). The analysis of hormone concentrations showed a correlation between the diagnosed trait and the value of TT (OR = 1.216; p = 0.046) and SHBG (OR = 1.020; p = 0.007). Conclusions: VAI and LAP have been shown to be good indicators for assessing erectile dysfunction in men over 60 years of age.

Evaluation of the Role of Visceral Adiposity Index in the Prediction of Erectile Dysfunction in Hyperlipidemia

“…Because the VAI formulates both structural and functional elements meaning that VAI contains both physical and metabolic parameters, so, VAI could be valuable index of both fat distribution and function. In agreement with our research, other reports of Akdemir et al (8), Aleksandra et al (12) showed that evaluation utilising indices like VAI, which showed that excessive visceral fat accumulation increases risk of developing ED, appears to be more reliable than using anthropometric parameters like BMI or WC. Consistent with our findings and that of the others, it has been demonstrated that VAI was independently related to cardiovascular events (8,13) .…”

“…Several research have examined utility of VAI to distinguish existence of ED in hyperlipidemia, have set cut-off points, and have advocated it as best predictor of ED given necessity for early detection and treatment of ED to limit its morbidity (8,11,12) . Several studies have demonstrated a connection among ED and measurements of fat accumulation such VAI.…”

Evaluation of Lower Urinary Tract Symptoms in Males and Urinary Incontinence in Females in Primary Health Care in Greece

“…The prevalence of moderate-to-severe ED was 63% within our population, rising to 84% in patients experiencing at least mild ED. The recorded prevalence of at least mild ED ranges from 63 to 68% in studies that employ the same screening questionnaire for ED in primary care settings [ 69 ] and in community-based research [ 70 ]. However, in primary care, symptoms of ED are often not fully disclosed due to various factors such as reporting bias, cultural influences, physicians’ failure to inquire about patients’ sexual health, and the social stigma surrounding the condition [ 71 ].…”

Análisis del grado de disfunción eréctil en adultos jóvenes de Tijuana, México

“…En ese sentido, la valoración inicial de los pacientes con de en su consulta de atención primaria debe incluir la búsqueda de factores de riesgo clínicos como la presencia de obesidad, ya que se trata de un factor modificable que influye en el desempeño sexual. 25,26 En cuanto al tratamiento, 30% de los hombres que usan medicamentos para de reportaron mal uso. 16 Un estudio realizado en Costa Rica, detectó que 35% de quienes consumen sildenafil son hombres entre 25 y 35 años.…”