Erectile dysfunction associated with undiagnosed prediabetes and type 2 diabetes in young adult males: A retrospective cohort study

Tucker, Jane; Salas, Joanne; Secrest, Scott; Scherrer, Jeffrey F.

doi:10.1016/j.ypmed.2023.107646

Cited by 5 publications

(4 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Multiple studies showed similar findings with a possibility of bidirectional relationship between both T2D and depression. 14,25,26 Longer T2D duration has been shown to increase the risk of ED in our study and earlier studies. 27,28 A higher level of education and monthly income were associated with less risk of ED in our study, but an earlier study showed no impact of educational level on seeking medical attention or compliance to ED treatment.…”

Section: Discussionsupporting

confidence: 79%

See 1 more Smart Citation

Erectile Dysfunction and Depression Prevalence Among Male Patients with Type II Diabetes

Alswat,

Almorgi,

Aljardahi

et al. 2024

JMDH

View full text Add to dashboard Cite

Background and Objective Patients with Type 2 Diabetes (T2D) are at substantial risk for developing erectile dysfunction (ED). The primary goal of this study was to assess the prevalence of ED and depression among T2D patients and the associated risk factors. Methods A cross-sectional study was conducted for adult T2D patients who had a routine clinic visit between January–August 2023. Structured questionnaires formed with two validated questionnaires – the International Index of Erectile Function short form (IIEF-5) and Patient Health Questionnaire (PHQ-9) – were used to screen for ED and depression, respectively. Results A total of 478 male patients with T2D with a mean age of 59.2 ± 10.8 years, mostly married, with long standing T2D were included. Hyperlipidemia followed by hypertension were the most reported comorbidities. Of the patients, 61.3% had reported no depression and were less likely to have ED or severe ED ( p <0.001) and more likely to be physically active and to report no smoking ( p <0.0001) when compared to those with depression. Fifty-two percent of the patients reported moderate and severe ED and those were older in age ( p = 0.031), had longer duration of T2D diagnosis ( p = 0.005), were more likely to have any comorbidities ( p <0.05), were less likely to have a university degree and higher income (both p <0.001), were less likely to be on oral hypoglycemic agents (OHA) ( p <0.001), had worse glycemic control parameters ( p = 0.463), were more likely to have positive urine microalbuminuria ( p = 0.019), and were less likely to be physically active ( p = 0.048) when compared to patients with no or milder degree of ED. Conclusion ED is highly prevalent in our study sample, with half of the patients having moderate to severe ED and being more likely to have depression. Older age, long-standing T2D, comorbidities, socioeconomic disadvantage, and sedentary lifestyle were all significantly associated with ED.

show abstract

Section: Discussionsupporting

confidence: 79%

“…Multiple studies showed similar findings with a possibility of bidirectional relationship between both T2D and depression. 14 , 25 , 26 …”

Section: Discussionmentioning

confidence: 99%

Erectile Dysfunction and Depression Prevalence Among Male Patients with Type II Diabetes

Alswat,

Almorgi,

Aljardahi

et al. 2024

JMDH

View full text Add to dashboard Cite

show abstract

“…Structured data extraction in a Microsoft Excel spreadsheet will be prepared and used. The extracted data form includes (1) study identification (last name of the primary author and year of publications), (2) the aim and the type of review, (3) prevalence of ED, (4) odds ratio and 95%CI of risk factors of ED, (5) the number of included primary studies within SRM, (6) the number of sample size included, (7) publication bias and quality assessment technique, (8) analytic model type (fixed effect/random) and (9) the conclusion of the SRM.…”

Section: Data Extraction and Managementmentioning

confidence: 99%

“…With the presence of diabetes, the likelihood of experiencing ED escalated significantly. [4][5][6] Diabetes combined with an increase in age increases the risk of ED. For instance, while 50-and 75-year-old healthy men faced a 20% and 68% probability of ED respectively, those with conditions such as diabetes encountered a higher risk, reaching 41% and 85% respectively.…”

Section: Introductionmentioning

confidence: 99%

Umbrella review protocol: Global burden and risk factors of erectile dysfunction in diabetic population

Kitaw,

Abate,

Tilahun

et al. 2024

Health Science Reports

View full text Add to dashboard Cite

BackgroundErectile dysfunction (ED) is no longer a whisper in the shadows; it's a rising tide threatening the sexual health of millions of men in different regions. This worrying trend shows no signs of slowing down, with projections claiming a staggering 322 million men globally could be affected in the near future. In the cases of diabetes, the condition worsens and has a potent cocktail of physical and psychological distress, chipping away at men's confidence, self‐esteem, and mental health. This urgent issue demands immediate attention and action. Thus, this umbrella review intended to estimate the current burden of ED and associated risk factors among diabetic patients in the global context.MethodsFollowing PRISMA guidelines will be searched for relevant Systematic Review and Meta‐analysis studies in PubMed, Embase, Scopus, Web of Science, Cochrane Database of Systematic Reviews, and Google Scholar. The quality of the included studies will be assessed using the new regress tool, the Assessment of Multiple Systematic Reviews 2 tool. To estimate the pooled prevalence of ED, we will employ a weighted inverse variance random‐effects model. We will further conduct subgroup analyses, assess heterogeneity and publication bias, and perform sensitivity analyses to strengthen the robustness of our findings. Prediction intervals will also calculated to estimate the range within which future observations will likely fall. In all statistical analyses, the statistical significance will be declared at p value < 0.05.DiscussionThis umbrella review of systemic review and meta‐analysis will be the first to systematically explore and integrate evidence regarding the burden of ED and associated risk factors in the diabetic population in a global context. By estimating the worldwide burden and identifying risk factors of ED in this population, the study will contribute to uncovering the hidden burden. Thereby, the issue will get international attention to reduce its consequences on the sexual health of the diabetic population. Besides, it will also provide input and direction for future research outlook.

show abstract

Erectile Dysfunction in Adolescents and Young Adults

Pantazis,

Franco,

Gitlin

2024

Curr Urol Rep

View full text Add to dashboard Cite

Erectile dysfunction associated with undiagnosed prediabetes and type 2 diabetes in young adult males: A retrospective cohort study

Cited by 5 publications

References 31 publications

Erectile Dysfunction and Depression Prevalence Among Male Patients with Type II Diabetes

Erectile Dysfunction and Depression Prevalence Among Male Patients with Type II Diabetes

Umbrella review protocol: Global burden and risk factors of erectile dysfunction in diabetic population

Erectile Dysfunction in Adolescents and Young Adults

Contact Info

Product

Resources

About