Erectile Dysfunction: A Review of Historical Treatments With a Focus on the Development of the Inflatable Penile Prosthesis

Abstract

Erectile dysfunction has been a concern for men since the beginning of written history. For many men it can lead to severe psychological distress and humiliation. The treatment of erectile dysfunction has advanced significantly over the past 200 years. Men today are presented with many more viable therapy options leading to improved efficacy and more satisfactory sex lives. The objective of this article is to explore historical options for the treatment of erectile dysfunction, with particular emphasis on the development and progression of the inflatable penile prosthesis.

Sexual Dysfunction and Gun Ownership in America: When Hard Data Meet a Limp Theory

“…According to Potts (2000, p.90), “the absence of—or difficulty in ‘achieving’ and ‘maintaining’— a robust ‘hard on’ in appropriate circumstances presents as a disastrous affliction in the male—an abnormality, a failure to stand up and be counted as a ‘real’ man.” In this context, many men experiencing erectile dysfunction (ED) never seek treatment for their condition, and those men who do often wait until their symptoms become too severe to ignore (Burns & Mahalik, 2007; Sand et al, 2008e). When men are willing to seek help, they are sufficiently motivated by their distress to entertain a wide range of potential treatments, including changes in diet and exercise, smoking cessation, cutting alcohol and drug use, periodontal treatment, herbs (e.g., red ginseng), acupuncture, natural hormones (e.g., DHEA) and amino acids (e.g., L-arginine), psychological counseling, prescription medications (e.g., Viagra), urethral suppositories, topical creams, testosterone replacement therapy, vacuum pumps, penile injection therapy, external penile prostheses, penile implants, vascular reconstructive surgery, stem cell therapy, platelet-rich plasma therapy, penile shockwave therapy, and penile transplants (Brubaker & Johnson, 2008; Burnett et al, 2020; Dong et al, 2019; Efesoy et al, 2018; Farook et al, 2021; Gurtner et al, 2017; Hatzimouratidis, 2007; Irfan et al, 2020; Ismail et al, 2019; Lau et al, 2008; Li et al, 2017, 2019; Mulhall et al, 2011; Punjani et al, 2018; Raina et al, 2007; Tsai et al, 2017; Ulloa et al, 2008; Walther et al, 2017; Wentzell et al, 2017).…”

An update on the best approaches to prevent complications in penile prosthesis recipients

“…Erectile dysfunction has long been a source of psychological, social, and physical distress for men, with treatments for this condition reported as far back as the early eighth century. 1 The concept of the penile prosthesis was first implemented in 1936 by Nicoli Bogoras, fashioned out of rib cartilage and bone. 2 Since that time, the penile prosthesis has undergone multiple iterations with variations in synthetic materials and surgical placement technique, in an attempt to decrease infection and erosion/extrusion risk.…”

Diagnosis of erectile dysfunction. The opinion of experts

“…Так как ЭД является полиэтиологическим заболеванием, то дифференциальная диагностика ее различных форм (психогенной, нейрогенной, васкулогенной) часто затруднена даже после детального сбора анамнеза, физикального обследования и изучения эндокринного статуса [5,[19][20][21][22]. Поэтому для визуализации ЭД урологи используют инструментальные методы диагностики [14,[23][24][25].…”

“…Некоторые специалисты выполняют кавернозографию на фоне фармакологически индуцированной эрекции. При этом стимуляция эрекции выполняется путем инъекционного интракавернозного введения 10 мкг простагландина Е [5]. Следовательно, пациент в момент одного исследования может получить две инъекции в одну анатомическую зону!…”