Erectile Dysfunction

Wylie, Kevan

doi:10.1159/000126623

Cited by 23 publications

(12 citation statements)

References 76 publications

(82 reference statements)

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“…They subsequently signed the informed consent and their anthropometric measurements were collected. To be more familiar with the treadmill walking on the noted speed (2 km/h), participants practiced walking on the treadmill for~5 min [35,36]. After that, Borg's 10-point scale [37] was explained to the participants to be able to report ratings of perceived discomfort (RPDs) for several body parts (see the Dependent Measures subsection).…”

Section: Procedures and Data Collectionmentioning

confidence: 99%

Development and Investigation of a Wearable Aid for a Load Carriage Task

Alabdulkarim

Farhan

Ramadan

2020

IJERPH

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Anterior load carriage tasks are common and can lead to musculoskeletal disorders such as lower back pain. The objectives of this study were to develop a wearable carriage aid and examine its effectiveness on physical demands while considering the potential moderating influence of the carried load. The study consisted of two within-subject factors: device and load. For the former, two levels were tested: with and without the device worn. For the latter, two loads were examined: 15 and 30% of each individual’s body mass. Sixteen participants walked on a treadmill for five minutes at a constant speed for each condition. Physical demands were quantified using objective (EMG-based) and subjective (discomfort) measures. Wearing the device reduced static and median anterior deltoid, trapezius, and biceps brachii muscle activations. Increasing the carried load increased most physical demand measures. Two significant Device × Load interactions were observed; for the anterior deltoid and trapezius median activation measures, the influence of increasing load was lower when the device was worn. While slightly increasing perceived discomfort in the lower back, wearing the device reduced shoulder, neck, and hand/wrist discomfort. While the study demonstrated a potential for the device, future work is required under more realistic and diverse testing conditions.

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Section: Procedures and Data Collectionmentioning

confidence: 99%

Development and Investigation of a Wearable Aid for a Load Carriage Task

Alabdulkarim

Farhan

Ramadan

2020

IJERPH

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“…Efficacy has also been demonstrated in subpopulations of men with ED including those with DM, neurological disorders including multiple sclerosis and spinal cord injury, hypertension, CAD, renal insufficiency, status postrenal transplant, and after nerve-sparing radical prostatectomy (reviewed in [106]). Several PDE5is, including tadalafil and sildenafil, may be used daily to either minimize as-needed dosing for sexual activity (tadalafil) in the setting of erectile preservation after surgery (tadalafil, sildenafil) or in the setting of men with concomitant LUTS and ED (tadalafil).…”

Section: Introductionmentioning

confidence: 99%

Current Diagnosis and Management of Erectile Dysfunction

Pastuszak

2014

Curr Sex Health Rep

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Erectile dysfunction (ED) affects a growing number of men in the USA and abroad, with significant impacts on sexual function and overall quality of life. The risk factors for ED are numerous and include a strong link to cardiovascular disease, such that men with ED should be screened for cardiovascular disease. The evaluation of men presenting with ED includes a comprehensive history and physical exam to aid in the identification of comorbidities as well as laboratory testing to evaluate hormone and lipid levels and sugar metabolism. Adjunct studies are also available, though their utility is often limited to specific subtypes of ED. Once the etiology of ED is established, treatment can be initiated using appropriate medical therapies, including phosphodiesterase type 5 (PDE5) inhibitors, and transurethral or intracavernosal therapies, with surgical intervention via revascularization or penile prosthesis placement in men demonstrating a lack of response to medical therapy. In all cases of ED, a psychogenic component is present and referral for psychological intervention with or without medical therapy should be considered.

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“…11 Despite the general agreement of previous investigators that the prevalence of impotence in diabetic men approximates 50 per cent, there is controversy surrounding the etiology of this problem. 12,13 Many clinicians have used the nocturnal penile tumescence (NPT) study to assist in the differential diagnosis of psychogenic from organogenic sexual dysfunction. The foundation of the test rests on the observations of regularly occurring erection cycles during sleep in healthy, sexually functional men, 14 and abnormally diminished or absent sleep-related erection cycles in organically sexually dysfunctional men 15 Measurements of NPT thus provide an objective and quantitative method for evaluating changes in erectile pattern.…”

Section: Introductionmentioning

confidence: 99%

The effect of Sildenafil citrate (ViagraTM) on the frequency, duration, and degree of nocturnal penile tumescence in diabetic neuropathic men

2009

Int J Diabetes Metab

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The present study deals with the effects of sildenafil citrate (Viagra) on the nocturnal sleep related erectile dysfunctions in diabetic neuropathic men. In this investigation 50 type 1 and 50 type 2 diabetic patients with and without an objective evidence of neuropathy, aged between 15 to 60 years with a duration of diabetes distributed over 1-20 years were included along with their age matched non diabetic controls. Subjects were evaluated for nocturnal penile tumescence (NPT) and rigidity testing and the effect of oral administration of 100 mg. of sildenafil citrate (Viagra) was noted on the abovementioned parameters. Both types of diabetic neuropathic patients exhibited a highly significant decrease in all nocturnal tumescence parameters including frequency, duration, and degree. However, both type 1 and type 2 patients without neuropathy showed a non-significant difference in the above-mentioned parameters than their respective control subjects, thus suggesting that impotence and altered nocturnal erectile responses are likely to be associated with an increased frequency to autonomic neuropathy in these patients irrespective of their type of diabetes. Treatment with oral administration of 100 mg. of sildenafil in both type 1 and type 2 diabetic neuropathic patients indicated significant increase (P<0.0001) in all the parameters of NTP and rigidity testing, however this difference was not significant in both types of diabetic patients without neuropathy before and after oral administration of sildenafil and when compared with their respective control subjects thus suggesting that oral administration of sildenafil citrate improves the quality of nocturnal erection in both type 1 and type 2 neuropathic group of patients. We thus conclude that sildenafil citrate is an effective first-line therapy for erectile dysfunction in diabetic men with impotence of neuropathic etiology. These results will improve our insight into the management of sexual disorders as part of diabetic care, and suggest guidelines for the prescription of Viagra in diabetic neuropathic patients.

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Erectile Dysfunction

Cited by 23 publications

References 76 publications

Development and Investigation of a Wearable Aid for a Load Carriage Task

Development and Investigation of a Wearable Aid for a Load Carriage Task

Current Diagnosis and Management of Erectile Dysfunction

The effect of Sildenafil citrate (ViagraTM) on the frequency, duration, and degree of nocturnal penile tumescence in diabetic neuropathic men

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