Erbb is linked to the alpha-globin locus on mouse chromosome 11.

Silver, Jonathan; Whitney, John P.; Kozak, Christine A.; Hollis, Gregory; Kirsch, IR

doi:10.1128/mcb.5.7.1784

Cited by 24 publications

(3 citation statements)

References 16 publications

(14 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Localization of Fis-J to mouse chromosome 7 proves that Fis-J is distinct from several oncogenes and common integration regions implicated in tumorgenesis by long-latency retroviruses but known to be on other chromosomes. These include myc (10), Myb (28), erbA and erbB (31,39), Int-i (22), Mlvi-i (15), Mlvi-2 (38), and Mis-i (R-Mo-int-i) (C. Kozak and P. Jolicoeur, unpublished data). Fis-i also appears to be distinct from Pim-1, a common integration region for Moloney virus in murine lymphomas, based on published restriction enzymes maps (5).…”

Section: Discussionmentioning

confidence: 99%

Common proviral integration region on mouse chromosome 7 in lymphomas and myelogenous leukemias induced by Friend murine leukemia virus

Silver¹,

Ca²

1986

J Virol

Self Cite

View full text Add to dashboard Cite

Friend murine leukemia virus (F-MuLV) induces a variety of hematopoietic neoplasms 2 to 12 months after inoculation into newborn mice. These neoplasms are clonal or oligoclonal and contain a small number of F-MuLV insertions in high-molecular-weight DNA. To investigate whether different tumors have proviral insertions in the same region, a provirus-cellular DNA junction fragment from an F-MuLV-induced myelogenous leukemia was cloned in XgtWES, and a portion of the flanking cellular DNA sequence was used in blot-hybridization studies of 34 additional F-MuLV-induced neoplasms. Three of these additional neoplasms (one myelogenous leukemia and two lymphomas) were found to have altered copies of the flanking cellular sequence. Restriction enzyme analysis of genomic DNA from these tumors revealed that in each case a proviral copy of F-MuLV had inserted into the same 1.5-kilobase region; all proviruses had the same orientation. Using mouse-Chinese hamster somatic cell hybrids, we mapped this common integration region, designated Fis-l, to mouse chromosome 7. Fis-l is distinct from three oncogenes on mouse chromosome 7, Ha-ras, fes, and Int-2, based on restriction enzyme analysis and blot hybridization. Therefore, Fis-I appears to be a novel sequence implicated in both lymphoid and myeloid leukemias induced by F-MuLV.

show abstract

Section: Discussionmentioning

confidence: 99%

Common proviral integration region on mouse chromosome 7 in lymphomas and myelogenous leukemias induced by Friend murine leukemia virus

Silver¹,

Ca²

1986

J Virol

Self Cite

View full text Add to dashboard Cite

show abstract

“…In con trast, genes on MMU II, whose homologs map to chromosomes other than 17 in the human (HSA), are located in the proximal region, e.g., Erbb (on HSA 7) and Uba («-globin complex) (on HSA 16) (Davisson and Roderick. 1981;Silver et al. 1985).…”

Section: Discussionmentioning

confidence: 99%

The murine <i>Hox-2</i> cluster of homeo box containing genes maps distal on chromosome 11 near the tail-short (<i>Ts</i>) locus

Münke

Cox

Jackson³

et al. 1986

Cytogenet Genome Res

View full text Add to dashboard Cite

Two probes derived from a mouse recombinant λ-clone (H24.1), that contains a sequence closely homologous to the Drosophila antennapedia homeo box, were mapped to mouse chromosome (MMU) 11 by filter hybridization of somatic cell hybrid DNA. This sequence is highly homologous to a human homeo box gene (HoX2) and appears to represent one of the two genes in the Hox-2 cluster previously assigned to MMU 11. To regionally map the Hox-2 cluster, we have carried out in situ hybridization of the two H24.1 probes and of an independently isolated Hox-2 probe. The autoradiographic silver grain distributions were similar in all three experiments with a peak over band 11 D. This region contains the locus for the tail-short (Ts) mutation which causes skeletal abnormalities in heterozygotes and early embryonic death in homozygotes.

show abstract

“…Four loci from this map, Hba, DZb-1, Hox-2, and Es-3, then were used as anchor loci for building a multilocus map of the same chromosomal region from Eu data. The loci Gfup and Cnp then were placed at their optimal positions in this second map (Table III [Taylor, 1981;Taylor et al, 1985;Silver et al, 1985;Cobb et al, 1987;Taylor, 1987;Buchberg et al, 1988; H a r t et al, 19881. The most likely order and spacing of the markers consistent with the overall map of the chromosome (Fig.…”

Section: Cnp a A A A L L L A L A L L L A L L A A O A A O A A O O A O mentioning

confidence: 99%

Chromosomal locations of genes encoding 2′,3′ cyclic nucleotide 3′‐phosphodiesterase and glial fibrillary acidic protein in the mouse

Bernier

Colman

D’Eustachio

1988

J of Neuroscience Research

View full text Add to dashboard Cite

Cyclic nucleotide phosphodiesterase (CNP) and glial fibrillary acidic protein (GFAP) are useful markers of myelin and astroglia, respectively. Two proteins with CNP activity are known to exist in brain and lymphoid tissues. They appear to be the products of several distinct but related messenger ribonucleic acid (mRNA) species. GFAP is a single protein encoded by a single mRNA. We have localized the GFAP gene to distal chromosome 11 in the mouse. There are two genetic loci identified by CNP probes, one is closely linked to the GFAP gene, and the other maps to chromosome 3.

show abstract

Erbb is linked to the alpha-globin locus on mouse chromosome 11.

Cited by 24 publications

References 16 publications

Common proviral integration region on mouse chromosome 7 in lymphomas and myelogenous leukemias induced by Friend murine leukemia virus

Common proviral integration region on mouse chromosome 7 in lymphomas and myelogenous leukemias induced by Friend murine leukemia virus

The murine <i>Hox-2</i> cluster of homeo box containing genes maps distal on chromosome 11 near the tail-short (<i>Ts</i>) locus

Chromosomal locations of genes encoding 2′,3′ cyclic nucleotide 3′‐phosphodiesterase and glial fibrillary acidic protein in the mouse

Contact Info

Product

Resources

About