Eradication of Aortic Infections With the Use of Cryopreserved Arterial Homografts

Vogt, Paul; Segesser, Ludwig K. von; Goffin, Yves; Niederhäuser, U; Genoni, Michele; KUNZLI, A; Lachat, Mario; Turina, Marko

doi:10.1016/s0003-4975(96)0045-4

Cited by 85 publications

(49 citation statements)

References 18 publications

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“…So far, cryopreserved aortic homograft showed its potential for in situ repair. 7,10,11,19) Durability of such repairs remains to be confirmed on the ground of higher patient volume with extended follow-up. Different methods for visceral debranching as well as optimal duration of preoperative and postoperative antibiotic treatment are still discussed.…”

Section: Resultsmentioning

confidence: 99%

“…The favorable long-term results of implanted cryopreserved human cardiac valves 17) have propelled the more common use of cryopreserved aortic homografts within the setting of aortic infections. 7,10,11) There is evidence which indicates that cryopreserved homografts are resistant to bacterial infection, 18,19) and that the immune response of the host may be limited. 19) In our patient wide debridement of the infected and necrotic tissue was performed prior to graft placement.…”

Section: Discussionmentioning

confidence: 99%

“…[6][7][8][9] Recently, cryopreserved aortic homografts regained importance due to advanced techniques of graft preservation and due to their favorable performance within the infected area. 7,10,11) If a visceral aortic segment is affected, reimplantation of involved arteries or visceral debranching is mandatory. However, different graft materials as well as a variety of treatment modalities are continuously under investigation.…”

Section: Introductionmentioning

confidence: 99%

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In Situ Repair of a Mycotic Suprarenal Aortic Aneurysm Using a Cryopreserved Aortic Homograft and Visceral Debranching in a Patient with Spondylodiscitis and Left Psoas Muscle Abscess

Petrunić

Meštrović

Lončarić

et al. 2013

ATCS

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We present a patient with ruptured suprarenal aortic aneurysm, involving origins of visceral and renal arteries. Associated spondylodiscitis and left psoas muscle abscess were also diagnosed. The patient was initially treated with antibiotics. Diagnostic survey showed progression of the aneurysm diameter and enlargement of the psoas muscle abscess. Surgical treatment using a cryopreserved aortic homograft with debranching of visceral arteries was performed. Different modalities of surgical repair within the infected aortic segment and the rationale for usage of cryopreserved homografts are considered. The importance of optimal timing for surgery is emphasized as well.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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In Situ Repair of a Mycotic Suprarenal Aortic Aneurysm Using a Cryopreserved Aortic Homograft and Visceral Debranching in a Patient with Spondylodiscitis and Left Psoas Muscle Abscess

Petrunić

Meštrović

Lončarić

et al. 2013

ATCS

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“…We observed such complications in all cases. We decided to use allogenic grafts stored according to the "cold ischemia" protocol, which are more durable than those prepared using the cryopreservation method of preservation in sub-zero temperatures (24,25).…”

Section: Discussionmentioning

confidence: 99%

Treatment of Vascular Prosthesis Infections — 15 Years of Experience

Kielar

Lewczuk

Tur

2010

Polish Journal of Surgery

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, 47 patients were treated at Department of General and Vascular Surgery Bródnowski Hospital due to symptomatic, late vascular graft infections. The most common local symptoms were groin abscesses, often with bleeding complications. All patients with diagnosed vascular prosthesis infections were treated operatively. Results. Fifty-three operations were performed, resulting in the regression of infection symptoms in 17 cases (63%), with 37% of cases leading to amputation. Mortality in the patients examined amounted to 37%; 46.4% of cases displayed recurrent infection. The period of hospital treatment oscillated between 12 to 221 days (av. 74 days). conclusions. 1. Aggressive operative treatment of vascular prosthesis infections is burdened by high percentages of recurrence and amputation. 2. Less radical operative treatment techniques yield similar results. 3. A uniform protocol for diagnosed vascular prosthesis infection is currently lacking.

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“…It also enables surgical reconstruction of hypogastric and deep femoral arteries, as indicated, thereby preventing the development of postoperative ischemic colitis or lower limb ischemia. However, mixed results have been reported regarding the efficacy of in situ replacement of infected aortic grafts with arterial www.intechopen.com Diagnosis, Screening and Treatment of Abdominal, Thoracoabdominal and Thoracic Aortic Aneurysms 236 homografts (Vogt et al, 1996). In one report, a 20% mortality was associated with this method of treatment (Speziale et al, 1997).…”

Section: Restoring Perfusion In Lower Limbsmentioning

confidence: 99%