Er-Bai-Tang decoction improved the movement disorders and neuronal injury in the Parkinson’s disease model rats via decreasing p38 MAPK pathway and improving the composition of intestinal flora
Abstract:Purpose:
Our previous study showed that Er-Bai-Tang decoction (EBT) could effectively improve Parkinson’s disease (PD) patients’ quality of life, sleep, mood, and cognitive disorders, but the mechanism of EBT to treat PD was unclear. So, our study aimed to explore the mechanism of EBT to treat PD via p38 mitogen-activated protein kinases (MAPK) pathway and intestinal flora.
Methods:
In our study, the PD rat model was established by subcutaneously injecting 2 mg/kg/d rot… Show more
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