1996
DOI: 10.1099/0022-1317-77-8-1719
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Equine rhinovirus serotypes 1 and 2: relationship to each other and to aphthoviruses and cardioviruses

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Cited by 92 publications
(118 citation statements)
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“…As the initiation of protein synthesis can take place at one of two AUG codons in FMDV and ERV1 (Sangar et al, 1987 ;Wutz et al, 1996), two forms of the L protein can be synthesized, the longer Lab and the shorter Lb form. As there is evidence that the Lb form is the biologically relevant one (Cao et al, 1995), it is this form of FMDV and ERV1 which is used in these studies.…”
Section: Resultsmentioning
confidence: 99%
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“…As the initiation of protein synthesis can take place at one of two AUG codons in FMDV and ERV1 (Sangar et al, 1987 ;Wutz et al, 1996), two forms of the L protein can be synthesized, the longer Lab and the shorter Lb form. As there is evidence that the Lb form is the biologically relevant one (Cao et al, 1995), it is this form of FMDV and ERV1 which is used in these studies.…”
Section: Resultsmentioning
confidence: 99%
“…Recent investigation of the genome structure of ERV serotypes 1 and 2 revealed that these viruses also possess an L proteinase of the FMDV type. However, sequence identity between all three viral proteinases is only between 18 % and 32 % (Wutz et al, 1996).…”
Section: Introductionmentioning
confidence: 99%
“…They are, therefore, also likely to elicit antibodies. Direct comparison of the known structure of FMDV VP1 with that predicted for ERAV VP1 (Wutz et al, 1996) shows that most of the predicted loops of ERAV VP1 are larger than those of FMDV. In particular, the bE-bF loop of ERAV, which contains a strong B cell epitope, is more than double the size of that in FMDV (32 compared to 14 aa in FMDV) and in the case of FMDV is not reported to contain any antigenic sites.…”
mentioning
confidence: 99%
“…ERAV is classified with foot-and-mouth disease virus (FMDV), albeit as a separate cluster, in the genus Aphthovirus, family Picornaviridae. ERAV shares many physico-chemical and biological properties with FMDV and the genome structures and sequences of the two viruses are also similar (Li et al, 1996;Newman et al, 1973;Plummer, 1963;Studdert & Gleeson, 1978;Wutz et al, 1996).…”
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confidence: 99%
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