Equine periocular neoplasia: Current concepts in aetiopathogenesis and emerging treatment modalities

Giuliano, Elizabeth A.

doi:10.1111/j.2042-3306.2010.tb05629.x

Cited by 41 publications

(45 citation statements)

References 86 publications

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“…There are numerous different treatments that can be used for SCC in horses including surgery, cryotherapy, radiotherapy, immunotherapy, photodynamic therapy, radiofrequency hyperthermia, laser surgery and chemotherapy (Giuliano 2010). The use of combination therapies is common practice.…”

Section: Discussionmentioning

confidence: 99%

“…2008). Squamous cell carcinoma is generally locally invasive and slow to metastasise (Giuliano 2010) and local recurrence is more commonly reported than metastasis. In the horse, SCC is reported to be the most common neoplasm of the eye and ocular adnexa and the second most commonly diagnosed tumour overall (Strafuss 1976; Lavach and Severin 1977; Sundberg et al .…”

Section: Introductionmentioning

confidence: 99%

“…1977; Junge et al . 1984; Giuliano 2010). Equine ocular and periocular SCC is typically invasive, resulting in discomfort and blindness if untreated (Fischer et al .…”

Section: Introductionmentioning

confidence: 99%

“…The tumour may affect one or more of the cornea; bulbar or palpebral conjunctiva; limbus; third eyelid and eyelids. Treatment generally involves surgical excision of the affected area or laser ablation, with or without adjunctive treatments such as chemotherapy, irradiation, cryotherapy, immunotherapy or photodynamic therapy (Giuliano 2010).…”

Section: Introductionmentioning

confidence: 99%

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Delayed metastasis of ocular squamous cell carcinoma following treatment in five horses

Mair

Sherlock

Pearson

2012

Equine Veterinary Education

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SummaryIdentification of regional and/or distant metastasis following treatment and local resolution of primary ocular squamous cell carcinoma (SCC) was observed in 5 horses. In all cases, identification of metastasis occurred at least 18 months following treatment of the primary ocular lesions. In 3 cases, invasion of blood or lymphatic vessels by neoplastic cells was identified in the excisional biopsies of the primary tumour. Two horses developed SCC at 2 or more separate sites. At the time metastases were identified, there was no evidence of local recurrence of the ocular tumour in any of the horses. These cases confirm the importance of long-term monitoring of horses for metastatic disease following treatment of ocular SCC even in the absence of local recurrence.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…1977; Junge et al . 1984; Giuliano 2010). Equine ocular and periocular SCC is typically invasive, resulting in discomfort and blindness if untreated (Fischer et al .…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Delayed metastasis of ocular squamous cell carcinoma following treatment in five horses

Mair

Sherlock

Pearson

2012

Equine Veterinary Education

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“…The same can be said for periocular sarcoids [64,79] . The lowest effective energy levels should be used in order to avoid excessive carbonization of surrounding tissue.…”

Section: Adnexal Tumorsmentioning

confidence: 91%

The use of lasers in veterinary ophthalmology: Recommendations based on literature

Spiess

2012

Photonics &Amp; Lasers in Medicine

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Lasers are routinely used in veterinary ophthalmology for the treatment of a number of ophthalmic conditions and diseases. In veterinary ophthalmology gas lasers and semiconductor lasers are primarily used. The most common indications for the use of diode and carbon dioxide lasers are presented and discussed. Diode lasers are primarily used in the treatment of glaucoma, either by transscleral cyclophotocoagulation or by endoscopic cyclophotocoagulation. Other indications are various forms of retinal detachments, as well as pigmented neoplasms of the uvea. An emerging field in veterinary ophthalmology is photodynamic therapy of periocular tumors. Carbon dioxide lasers are used for pars plana vitrectomies and surgical excision of ocular tumors. AbstractLasers are routinely used in veterinary ophthalmology for the treatment of a number of ophthalmic conditions and diseases. In veterinary ophthalmology, gas lasers (CO 2 lasers) and semiconductor lasers (diode lasers) are used primarily, but the therapy of posterior capsular opacifi cation with the Nd:YAG laser has also been described. This paper presents and discusses the most common indications for the use of the diode and CO 2 lasers. Diode lasers are mainly used in the treatment of glaucoma, either by transscleral cyclophotocoagulation or by endoscopic cyclophotocoagulation. Other indications are various forms of retinal detachments, as well as pigmented neoplasms of the uvea. An emerging fi eld in veterinary ophthalmology using diode lasers is photodynamic therapy of periocular tumors. CO 2 lasers are used for pars plana vitrectomies and surgical excision of ocular tumors.Keywords: diode laser; carbon dioxide laser; ophthalmic surgery; animal . ZusammenfassungLaser werden in der Veterin ä r-Ophthalmologie zur Behandlung unterschiedlicher Augenver ä nderungen und -erkrankungen regelm ä ß ig eingesetzt. Es kommen haupts ä chlich Gas (CO 2 )-und Halbleiterlaser (Diodenlaser) zur Anwendung, aber auch der Nd:YAG-Laser wird eingesetzt, bspw. zur Therapie des Nachstars (posterior capsular opacifi cation, PCO). Im vorliegenden Artikel werden die h ä ufi gsten Indikationen zur Verwendung von Dioden-und CO 2 -Lasern vorgestellt und diskutiert. Diodenlaser werden haupts ä chlich zur Therapie des Glaukoms eingesetzt, sei es mittels transskleraler oder mittels endoskopischer Zyklophotokoagulation. Andere Indikationen sind verschiedene Formen der Netzhautabl ö sung sowie pigmentierte Tumoren der Uvea. Ein neu aufkommendes Einsatzgebiet f ü r Diodenlaser ist die photodynamische Therapie von periokul ä ren Tumoren. CO 2 -Laser werden in erster Linie f ü r die Pars-plana-Vitrektomie beim Pferd und zur Exzision von Tumoren verwendet.Schl ü sselw ö rter: Diodenlaser; CO 2 -Laser; Augenchirurgie; Tier.

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Diseases of the adnexa and nasolacrimal system

Giuliano¹

2016

Equine Ophthalmology

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Equine periocular neoplasia: Current concepts in aetiopathogenesis and emerging treatment modalities

Cited by 41 publications

References 86 publications

Delayed metastasis of ocular squamous cell carcinoma following treatment in five horses

Delayed metastasis of ocular squamous cell carcinoma following treatment in five horses

The use of lasers in veterinary ophthalmology: Recommendations based on literature

Diseases of the adnexa and nasolacrimal system

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