Equine marker genes: Polymorphism for plasminogen

Abstract

SummaryPolymorphism for two autosomal alleles of equine plasminogen, PLG1 and PLG2, was demonstrated in plasma by isoelectric focusing and immunofixation, with a goat anti‐human plasminogen antibody. The frequency of PLC2 was 0.16 in 150 Standardbreds, 0.20 in 96 Thoroughbreds, and 0.39 in 32 Shetland ponies. No evidence for linkage of PLG with any of 13 marker loci was found.

The red cell ‘X’‐protein system in goats: evidence for a third allele in a Malaysian breed

“…It was suggested that the Eso allele either changes the enzymatic characteristics of esterase with regard to substrates and inhibitors, or that it gives rise to an enzymatically inactive protein (Gahne 1966). Weitkamp (1987) described a silent allele for a minor red cell protein of unknown function and identity in equine. Likewise in the present study the X" allele may be assumed to be recessive, possibly as a consequence of a defective or absent substance whose phenotypic effect can be masked in the heterozygote by the functioning X 1 and X 2 substances.…”

Standardbred stallion gene transmission for twelve protein systems: evidence for selection in trotters

“…For horses from which only plasma samples were available, PGM was typed from plasma using the IEF system of Gahne et al (1980), stained with the same reagents used for typing red cell PGM. Plasminogen (PLG) was typed as described by Weitkamp et al (1983). Malic enzyme (ME1 ) was typed in either red cells or plasma by the procedures referenced in Weitkamp et al (1982a).…”