Equine Cutaneous Amyloidosis Derived from an Immunoglobulin λ-Light Chain. Immunohistochemical, Immunochemical and Chemical Results

Prion and prion-like diseases in animals

“…It appears in a heterogeneous range of diseases, associated with neoplasias (such as lymphoma (Gliatto and Alroy, 1995) or plasmocytoma (Linke et al, 1991) in horses) or even producing odontogenic tumors in cats and dogs (Gruys, 2004;Snyder et al, 2011).…”

Diseases of the Equine Urinary System

“…6,7,9,10 Idiopathic immune-mediated and non-immune-mediated glomerulonephritides have been sporadically reported as well. [11][12][13] Glomerular amyloidosis in horses is unusual. 3,14 Clinically, horses presenting with glomerular disease suffer from symptoms that could include anorexia, weight loss, depression, or dependent edema.…”

Amyloidosis in Domestic Animals: Pathology, Pathogenesis, Gross and Microscopic Lesions and Clinical Findings

“…Some forms of naturally occurring transmissible spongiform encephalopathies such as chronic wasting diseases (CWD), are characterized by amyloid plaques in the brain in addition to the intraneural vacuolation (Snyder, 2007). In horses, localized cutaneous amyloidosis is described in association with lymphoma (Gliatto & Alroy, 1995), extramedullary plasmacytoma (Linke et al, 1991) and liver amyloidosis in serum-producing horses (Abdelkadir, et al, 1991). Local amyloidosis associated with plasma cell dyscrasia or focal extramedullary plasmacytoma occurs on the skin and along intestinal tracts in dogs (Fig.…”