Equilibrium and structural studies on metal complexes of carbohyrates and their derivatives

Theoretical study of the experimental coordination behavior of N-(2-aminophenyl)-d-glycero-d-gulo-heptonamide to Hg(II) ion

“…The FAB + mass spectra of a fresh sample of the solution from the 1:1 experiment showed the peak corresponding to the molecular ion of the complex [Hg(adgha) 2 ] + m/z 833 (M + , 8%), and two other peaks at m/z 815 (35) and m/z 797 (5) suggesting the formation of the [Hg(adgha)(ghbz)] + and [Hg(ghbz) 2 ] + complexes as a result of the loss of one and two water molecules, respectively. Additionally, at m/z 601 (5) appears a peak that corresponds to [Hg(adgha)(DMSO-d 6 )] + and at m/z 516 (7) to [Hg(adgha)] + . It was also possible to observe a very intense peak at m/z 299 (78) that might correspond to the molecular ion of the free ghbz.…”

“…14 All other chemicals were purchased from commercial sources and used as received. Solution NMR ( 1 H, 13 C) spectra were recorded on Varian Gemini 200 spectrometer in DMSO-d 6 . Chemical shifts are reported in ppm (d) downfield from internal TMS.…”

“…4,5 Although coordination chemistry plays a central role in these processes, relatively few well-characterized metallic complexes with carbohydrate ligands have been reported. 6 The development of carbohydrate coordination chemistry requires a thorough understanding of the behavior of these compounds as ligands. [7][8][9][10] The study of carbohydrates coordination compounds is a challenge, because single crystals suitable for X-ray diffraction measurements are difficult to obtain and conventional NMR spectroscopic measurements are not always able to discern the coordination mode.…”

A Novel Synthesis of 2‐Amino‐2‐deoxy‐D‐gluconic Acid and Its Complexation with Cu(II) in Alkaline Medium

“…On introduction of a carboxylic or amino group (or both) into a sugar molecule, the complex-forming ability is enhanced by several orders of magnitude. 13 The excellent chelating ability of these sugar-type ligands suggests their use as sequestering agent for both essential and toxic metal ions present in biological media.…”

Metal–N-saccharide chemistry: synthesis and structure determination of two Cu(II) complexes containing glycosylamines

“…Yield 1.19 g (52%); )163.6 O(9)-C(9)-C(10)-C (11) 170.8 Table 5. Hydrogen-bond data for 1 (12) 1.28 (11) 1.88 (11) 2.884 (6) 131 (8) Àx; y À 1=2; Àz O(14)-H(21)Á Á ÁO (9) 0.75 (5) 1.95 (5) 2.697 (5) 171 (5) Àx; y þ 1=2; 1 À z O(12)-H(22)Á Á ÁO (8) 0.73 (8) 2.18 (8) 2.908 (7) 175 (9) Àx; y þ 1=2; 1 À z O(10)-H(25)Á Á ÁO (2) 0.65 (7) 2.43 (9) 2.891 (5) 130 (10) x À 1; y; z þ 1 O(9)-H(26)Á Á ÁO (3) 0.88 (6) 1.91 (6) 2.734 (6) 155 (5) x À 1; y; z þ 1 O(8)-H(29)Á Á ÁO (16) 0.52 (6) 2.23 (6) 2.731 (6) 164 (10) Àx; y À 1=2; Àz O(3)-H(10)Á Á ÁCl (1) 0.54 (6) 2.53 (8) 2.998 (7) 147 (8) x; y; À1 þ z O(16)-H(15)Á Á ÁCl (1) 0.96 (5) 2.25 (7) 3.125 (6) 152 (7) 1 À x; y þ 1=2; Àz mp 90-92°C; Anal. Calcd for C 24 H 48 N 4 O 15 Cl 2 Cu: C,37.58;H,6.31;N,7.30;Cu,8.28.…”