Equilibrium and Non‐equilibrium Reaction Schemes for Prebiotic Polymerization of Ribonucleotides
Varun Kitson,
Quentin Sanders,
Avinash V. Dass
et al.
Abstract:The RNA World theory for the origin of life requires polymers to be generated initially by abiotic reactions. Experiments have studied polymerization of 5′‐monophosphates, 2′,3′‐cyclic phosphates, and 5′‐triphosphates. We consider theoretical models of polymerization in solution illustrating the differences between these cases. We consider (i) a basic model where all monomers undergo reversible joining and breaking; (ii) a model where 2′,3′‐cyclic phosphates can join, and breaking regenerates the cyclic phosph… Show more
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