Water block or invasion of water into the pores of reservoir forms during the operations of water-based drilling, injection, many perforations, completion fluids, and some other particular processes in the reservoir (such as fingering and conning). Subsequently, the alteration in the shape or composition of the fine particles such as clay (water-wet solids), as a result of the stress on it, in the flow path of the second phase can lead to the permeability decline of reservoir. Consequently, the solvents such as surfactants (as demulsifiers) to lower the surface tension as a phenomenon associated with intermolecular forces (known as capillary action) during flowback are consumed to avoid the emulsions and sludge mostly in the near-wellbore zone or undertreatment and under-injection radius of the reservoir. However, in addition to surging or swabbing the wells to lower the surface tension, using solvents as the wettability changing agent along with base fluid is a common method in the water block elimination from the wellbore, especially in the low permeability porous media or the reservoirs latter its average pressure declined below bubble point. For more profitability, after using solvents in various reservoir characterizations, the trend of their behavior variations in the different lithologies is required to decide on the removed damage percentage. The investigations on this subject involve many experimental studies and have not been presented any mathematical formulas for the damage of water block in the water, oil, and gas reservoirs. These formulas determine selection criteria for the applied materials and increase variable performance. An integrated set of procedures and guidelines for one or more phases in a porous media is necessary to carry out the step-by-step approach at wellhead. Erroneous decisions and difficult situations can also be addressed in the injection wells or saltwater disposal wells, in which water block is a formation damage type. Misconceptions and difficult situations resulting from these injuries can increase water saturation in borehole and affect the fluid transmissibility power in reaching far and near distances of the wellbore, which results in injection rate loss at the wellhead. Accordingly, for the equations of water block here, a set of variables, of a particular domain, for defining relationships between rock-and fluid-based parameters are required. For these equations, at first, the structural classifications of fracture and grain in the layers (d 1 ,d 2 , and d 3) are defined. Afterward, the equations of overburden pressure (P ob) for a definite sectional area surrounding the wellbore for any lithology (in the three categories relative to porosity) are obtained by these structural classifications and other characteristics of rock and fluid. Naturally, prior to equations of overburden pressure in 2 Oil and Gas Wells