Observed temperatures of transiently accreting neutron stars in the quiescent state are generally believed to be supported by deep crustal heating, associated with nonequilibrium exothermic reactions in the crust. Traditionally, these reactions are studied by considering nuclear evolution governed by compression of the accreted matter. Here we show that this approach has a basic weakness, that is that in some regions of the inner crust the conservative forces, applied for matter components (nuclei and neutrons), are not in mechanical equilibrium. In principle the force balance can be restored by dissipative forces, however the required diffusion fluxes are of the same order as total baryon flux at Eddington accretion. We argue that redistribution of neutrons in the inner crust should be involved in realistic model of accreted crust.