Epstein-Barr Virus Nuclear Protein 2-Induced Activation of the EBV-Replicative Cycle in Akata Cells: Analysis by Tetracycline-Regulated Expression

Fujiwara, Shigeyoshi

doi:10.1007/978-3-642-56515-1_3

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The Molecular Mechanisms Of Ebv Infection and The Effects On1

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2012

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“…It was found to associate with the chromatin and nuclear matrix (32) and has been identified previously as a transcriptional regulator of the expression of cellular and EBV genes including AML-2 (RUNX3), CD21, CD23, c-MYC, EBI-1, Hes-1, LMP1, and LMP2A (19,44,51,80,85,130,152,255,278,303,304). Their mechanism of regulation is suggested by the binding of EBNA2 with cellular transcription factors RBPJ, CBF-2/AUF1 or Spi-1/PU.1 to specific response elements of each promoter (137).…”

Section: The Molecular Mechanisms Of Ebv Infection and The Effects Onmentioning

confidence: 95%