Epstein-Barr virus in AIDS-related primary central nervous system lymphoma

Detection of Toxoplasma Gondii DNA in Primary Intraocular B-Cell Lymphoma

“…Additionally, EBV DNA was detected in all five patients. As EBV has been linked to lymphoma in AIDS patients (22,23), it is unclear what role T. gondii may have played in the malignant transformation of the CNS lymphoma of the AIDS patient in Tachikawa and colleagues' report. Furthermore, in that study, it was not clarified whether T. gondii DNA was present in lymphoma cells or whether lymphoma cells were present in the tested CSF.…”

Epstein-Barr virus transformation: involvement of latent membrane protein 1-mediated activation of NF-κB

“…For most people, latent infection is innocuous due to constant immune surveillance of infected cells. In contrast, immune-compromised individuals may incur a lymphoproliferative disease due to the lack of a continued immune response to EBV (Hamilton-Dutoit et al, 1991Ho et al, 1985;MacMahon et al, 1991; reviewed in Rickinson and Kie , 1996).…”

Monographs on the Evaluation of Carcinogenic Risks to Humans

“…Iymphomas of the central nervous system were positive for EBV in most studies (MacMahon et al, 1991;Hamilton-Dutoit et aL., 1993a;CamiIeri-Broet et al, 1995; Cinque et aL., 1993) (see Table 20). However, GuntheI et al (1994) reported a few primary Iymphomas of the central nervous system that were negative for EBV by a sensitive PCR assay.…”