Epstein-Barr virus associated gastric carcinoma: a report from Iran in the last four decades

Abstract

Background: Epstein-Barr virus has been proved to be associated with many of the human malignancy including gastric carcinoma, one of the most important human malignancies in the world. There has been no study about the presence of EBV in gastric adenocarcinoma in Iran.

Meta-analysis of the relationship between Epstein-Barr virus infection and clinicopathological features of patients with gastric carcinoma

“…Twenty-two articles [4,8,[13][14][15][16][17][18][19][22][23][24][25][26][27][28][29][30][31][32][33][34] were obtained based on the above-mentioned criteria . The samples assayed were collected from 1969 to 2006, and the geographical distribution of the samples examined included 10 countries, i.e., the USA, Brazil, China, Iran, Japan, Kazakhstan, Malaysia, Korea, Mexico, and the Netherlands.…”

The Application of Weibull Regression in the Study of Survival Patients Evolved by Gastric Cancer Referred to Imam Khomeini Hospital of Sari (Northern Iran)

“…The results of the current study showed that the stage and metastasis were the significant variables on the survival of the patients affected by gastric cancer, and the highest age was obtained in the seventh decade of life, and also the most common type of cancer diagnosed was adenovirus Published anatomical carcinoma and cardiac and antrum of the stomach, and then according to Zhou et al (3,11), Weibull model was used for the survival of stomach cancer patients in a retrospective study. Hence, 1715 patients with colorectal cancer were examined regarding their age at diagnosis, gender, family history, drug history, tumor location, tumor size, lymph node status, and tumor stage Pathology and depth, which were all selected as potential factors corresponding with the only variable of pathological stage study.…”

“…The results of the study conducted by Esmaeeli (48) in Mazandaran province (North of Iran) and by Yazdanbod (28) in Ardabil province (in the north-west of Iran) are almost consistent with the current study, but the findings of studies done by Zera'ati (49) In the present study, the method of treatment was not determined as a factor affecting the patients' survival. But in the studies done in Northern America (53), Sun in China (11,54) and in the Europe (55), a positive effects of complementary chemotherapy and chemotherapy-radiotherapy is reported leading to the patients' survival. Finally, this study showed that the survival of the patients involved with the gastric cancer referring to the Touba Treatment Clinic Center of Sari is in low level, which might be because of the few facilities for on time diagnosis and any strategic program to control this kinds of cancers in Mazandaran province.…”

“…Despite this census, new cases equal to 21260 have been diagnosed along the US, and 11210 of the American cancerous cases died in the year 2007. The cancer occurrence is still high in some countries like Japan, China, Chile, and Ireland (10,11). Also in Iran, gastric cancer is ranked three as the cause of death after road accidents and cardiovascular diseases, and is considered as one of the most important health and cure problems.…”

Trend of Incidence of Gastric Cancer in Sistan and Baluchestan Province, Iran

“…Despite the significant decline in the incidence of gastric cancer in the world, especially European countries such as Spain and Italy, which is as the result of the substantial improvement of living conditions, it is passing an ascending trend in developing countries like Iran. Some of this incidence increase is related to improved cancer registry system [35] in the country, and perhaps some proportion of that is due to changes in risk factors of this cancer such as an increase in H. pylori infection [36][37][38][39][40][41]. Surveying the distribution of sex frequency of these patients in the study period shows that the incidence of this cancer is always higher in men.…”