Epo Response to 24 HRS of Artificial Hypobaric Hypoxia Predicts Epo Response to Natural Altitude

Physiological and Biological Responses to Short-Term Intermittent Hypobaric Hypoxia Exposure: From Sports and Mountain Medicine to New Biomedical Applications

“…The reduced performance in sporting events with a high aerobic component was evident, while participants in competitions with a clear anaerobic character saw no decline in their performance, and some even beat their records (Di Prampero et al, 1970 ). As a consequence, stays at high altitude and other artificial hypoxia exposure strategies in athletes were subject to intense study; a wide range of strategies, from permanent stays at moderate or high geographic altitudes (Antezana et al, 1994 ; Richalet et al, 1994 ) to different patterns of intermittent exposure (Levine and Stray-Gundersen, 1997 ; Chapman et al, 1998 ; Rodríguez et al, 1999 ; Casas M. et al, 2000 ; Karlsen et al, 2001 ; Stray-Gundersen et al, 2001 ; Ge et al, 2002 ; Lundby et al, 2007 ; Richalet and Gore, 2008 ) were examined. Noticeable differences in protocols and hypoxia exposure methods led to intense debate on the usefulness of intermittent hypoxia exposure for elite athletes, given that hypoxic dose and interindividual variability represent two of the main constraints (Chapman et al, 1998 ; Casas H. et al, 2000 ; Julian et al, 2004 ; Gore et al, 2006 ; Wilber et al, 2007 ; Truijens et al, 2008 ; Rodríguez et al, 2015 ).…”