Epizootiology of Trichinellosis in Pigs and Wild Boars in Western Romania, 1998–2011

Borza, Claudia; Neghină, Adriana Maria; Dumitrașcu, Victor; Ţîrnea, Livius; Calma, Crenguta Livia

doi:10.1089/vbz.2011.0955

Cited by 9 publications

(7 citation statements)

References 13 publications

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“…Frequently, people from urban areas buy their own pigs, which are raised and slaughtered by their friends or relatives in the countryside ( 13 ). Between 1998 and 2011, in Western Romania, the annual average number of infected pigs on farms was 48.6 and in private households 29.1( 17 ).…”

Section: Discussionmentioning

confidence: 99%

Trichinellosis in hospitalized patients from Western Romania: A retrospective study

et al. 2021

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Trichinellosis is a public health problem and an economic issue in porcine animal production and food safety. The aim of this retrospective study was to evaluate the current epidemiologic, laboratory, clinical and therapeutic aspects of human trichinellosis in Western Romania. We retrospectively investigated the medical records of patients hospitalized in infectious diseases hospitals from three counties in Western Romania, between January 1st, 2012 and December 31st, 2016. A total of 83 patients diagnosed with trichinellosis were included in the study. Pork meat was the food source of infection in 76 (91.6%) patients and wild boar meat in 4 (4.8%). Patients were aged between 2 and 78 years; 48 (57.8%) were males and 27 (32.5%) came from an urban area. The most frequent symptoms included myalgia in 66 (79.5%) patients, fever in 55 (66.3%), eyelid edema in 40 (48.2%) and asthenia in 35 (42.2%). Two patients died and the others had favorable outcome. Although the number of reported cases has decreased in the past years, trichinellosis remains an important public health problem in Western Romania. Educational programs for both swine breeders and consumers are imperative, and implementation of strict hygienic measures aimed to control infection transmission are strongly recommended.

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Section: Discussionmentioning

confidence: 99%

Trichinellosis in hospitalized patients from Western Romania: A retrospective study

et al. 2021

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“…The data were collected from the Veterinary Public Health Department of Timiș County and show a low prevalence rate in wild boars, meaning this species of animal exhibit a minor role in the local sylvatic life cycle of Trichinella ( Fig. 1 ) ( Borza et al, 2012 ).…”

Section: Prevalence Of Trichinella Spp Infections ...mentioning

confidence: 99%

A review of Trichinella species infection in wild animals in Romania

Gherman

Boros

Băieș

et al. 2022

Food and Waterborne Parasitology

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“…Candesartan is an inhibitor of the renin-angiotensinaldosterone system and part of the ARB family. It is used as a pro-drug, mainly in treating hypertension and heart failure [7,13,14,31]. Candesartan is employed as monotherapy or in combination with other drugs to reduce cardiovascular morbidity and mortality.…”

Section: Ef (%)mentioning

confidence: 99%

The Plasma Level of Soluble Endoglin in Hypertensive Patients Undergoing Long-Term Treatment With Candesartan

BUDA¹

2022

FARMACIA

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Endoglin is a transmembrane glycoprotein involved in regulating endothelial function and homeostasis. We investigated the effect of candesartan compared with that of different regimens of blood pressure (BP)-lowering agents on the plasma level of soluble endoglin (sEng), a biomarker involved directly in endothelial homeostasis. A total of 395 patients were enrolled, of which 129 had normal BP (group A, control group), 133 were hypertensive patients treated with candesartan (8, 16, or 32 mg/day) in monotherapy (group C) and 133 were hypertensive patients treated with different types of antihypertensive agents (beta-blockers, calcium-channel blockers, diuretics) as monotherapy (group B). Classical methods of assessing endothelial damage (flow-mediated dilatation, intima-media thickness) as well as other biochemical parameters and investigations were undertaken. Correlations with the plasma level of sEng were performed. A lower plasma level of sEng was found in patients undergoing long-term BP-lowering treatment with candesartan compared with that in hypertensive patients undergoing longterm treatment with beta-blockers, calcium-channel blockers, or diuretics (p < 0.001). Diastolic BP and the blood urea nitrogen (BUN) levels were protective factors for sEng. The end-diastolic diameter of the left ventricle and neutrophil count were risk factors for soluble endoglin and thus for endothelial dysfunction. By quantifying a glycoprotein involved in endothelial function/homeostasis regulation, sEng, could be a specific biomarker of vascular and cardiac lesions and predict the efficacy of antihypertensive treatment. RezumatEndoglina solubilă (sEng) este o glicoproteină transmembranară implicată în reglarea funcției și a homeostaziei endoteliale. 395 de pacienți au fost înrolați în studiu, dintre care 129 cu tensiunea arterială (TA) normală (grupul A), 133 pacienți hipertensivi sub tratament cu candesartan (8, 16 sau 32 mg/zi) în monoterapie (grupul C), iar 133 au fost pacienți hipertensivi sub alte regimuri de tratament antihipertensiv în monoterapie (grupul B). S-au evaluat leziunile endoteliale prin metode clasice, și au fost efectuate investigații biochimice, toate acestea fiind corelate cu nivelul plasmatic al sEng. Un nivel mai scăzut al sEng plasmatice a fost găsit la pacienții sub tratament cronic cu candesartan, comparativ cu cel al pacienților sub tratament cronic cu alte clase farmacologice (p < 0,001). TA diastolică și nivelul acidului uric au fost identificați ca factori de protecție pentru sEng. Diametrul end-diastolic al ventriculului stâng și numărul de neutrofile au fost identificați ca factori de risc pentru sEng și, prin urmare, pentru disfuncția endotelială. În concluzie, endoglina solubilă ar putea fi un biomarker specific al leziunilor vasculare și cardiace, ce ar putea cuantifica eficacitatea tratamentului antihipertensiv.

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Epizootiology of Trichinellosis in Pigs and Wild Boars in Western Romania, 1998–2011

Cited by 9 publications

References 13 publications

Trichinellosis in hospitalized patients from Western Romania: A retrospective study

Trichinellosis in hospitalized patients from Western Romania: A retrospective study

A review of Trichinella species infection in wild animals in Romania

The Plasma Level of Soluble Endoglin in Hypertensive Patients Undergoing Long-Term Treatment With Candesartan

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