“…1,3,6 Epitrochlear lymphadenopathy is generally painless, and historically, this well-recognized evidence of secondary syphilis prompted use of the so-called sailor's handshake. 7 That is, a person would check a potential sexual partner for syphilis by shaking hands with one hand while grasping the area above the elbow with the other, surreptitiously assessing for the presence of swollen glands. Histopathology, likely far more reliable, can reveal marked follicular lymphoid hyperplasia, capsular thickening, histiocytosis, and microabscesses.…”