Epithelioid sarcoma. An analysis of fifty-one cases.

Bos, Gary D.; Pritchard, Douglas J.; Reiman, Herbert M.; Dobyns, James H.; Ilstrup, Duane M.; Landon, Gene

doi:10.2106/00004623-198870060-00011

Cited by 133 publications

(133 citation statements)

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“…Distant metastasis at the time of diagnosis is widely accepted as a predictor of worse prognosis [3,5,6,8,11,16,21,28,36,39]. Our analysis supported this commonly held belief and patients with local and regional disease did better than patients with distant disease.…”

Section: Discussionsupporting

confidence: 81%

“…Male gender also has been associated with a poorer outcome, whereas others have reported conflicting evidence [5,8,13,28,36]. We observed no survival benefit associated with female gender on univariate analysis.…”

Section: Discussioncontrasting

confidence: 65%

“…The largest series to date by Chase and Enzinger [8] in 1985 described 241 patients from multiple centers. Two other larger series came from the Royal Marsden Hospital and the Mayo Clinic [5,27]. Although the numbers of patients are larger in these series than in other reported series, they are limited in statistical power.…”

Section: Introductionmentioning

confidence: 91%

“…Previous reports describing the outcomes of patients with ES have limited statistical power owing to the small number of patients in each series [3][4][5][6][7]. The largest series to date by Chase and Enzinger [8] in 1985 described 241 patients from multiple centers.…”

Section: Introductionmentioning

confidence: 99%

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Prognostic Factors for Survival in Patients with Epithelioid Sarcoma: 441 Cases from the SEER Database

Jawad

Extein²,

Min

et al. 2009

Clinical Orthopaedics &Amp; Related Research

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Current stratification of prognosis in patients with epithelioid sarcoma (ES) is based largely on data reported by individual centers with a limited number of patients. We sought to identify the important prognostic parameters using the Surveillance, Epidemiology, and End Results (SEER) database. We identified 441 patients with ES in the database and extracted information regarding patient demographics and clinical characteristics. KaplanMeier, log-rank, and Cox regression were used for analysis.

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Section: Discussionsupporting

confidence: 81%

Section: Discussioncontrasting

confidence: 65%

Section: Introductionmentioning

confidence: 91%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Prognostic Factors for Survival in Patients with Epithelioid Sarcoma: 441 Cases from the SEER Database

Jawad

Extein²,

Min

et al. 2009

Clinical Orthopaedics &Amp; Related Research

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show abstract

“…Mineralization is seen on plain radiographs in 30% of patients with synovial sarcoma [2]. MRI often shows a heterogeneous appearance, with low signal intensity on T1-weighted images, high signal intensity on T2-weighted images, and contrast enhancement [1]. Unlike GCTTS, approximately 44% of synovial sarcomas have foci of hemorrhage observed on MR images, but both entities frequently are found in close proximity to a joint [9].…”

Section: Discussion and Treatmentmentioning

confidence: 99%

Orthopaedic Case of the Month: A 51-year-old Man with a Painless Wrist Mass

Nicolescu

Clifford

Robinson

et al. 2013

Clinical Orthopaedics &Amp; Related Research

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A 51-year-old right-hand dominant man was evaluated for an enlarging, painless left wrist mass of 2 months duration. The patient reported no recent injury or antecedent trauma and denied any local neurologic symptoms, fevers, chills, or changes in weight.Physical examination revealed a nontender, 3 9 2-cm firm, mobile mass overlying the volar aspect of the left distal ulna. There was no rash or other identifiable overlying skin changes, and the lesion did not transilluminate. The patient had normal strength and ROM, and sensation to light touch was intact in all three nerve distributions. There was a negative Tinel's sign and the mass was nonpulsatile with a normal vascular examination.AP and lateral views of the left wrist ( Fig. 1) and MRI of the wrist (Fig. 2) were obtained.

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Extremity Epithelioid Sarcoma

et al. 1991

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Amputation has traditionally been advised for extremity epithelioid sarcoma because of its pattern of innocuous presentation and relentless soft-tissue and nodal metastasis. To assess the role of amputation in extremity epithelioid sarcoma, we reviewed our experience with 42 patients treated between 1961 and 1986. On presentation with localized primary tumor (n = 18), nine of 11 patients who underwent wide local excision and four of six patients who underwent excisional biopsy were free of disease, and one patient who underwent amputation died. After presentation with localized recurrence (n = 12), four of six patients who underwent wide local excision and two patients who underwent excisional biopsy were free of disease; three other patients who underwent wide local excision had margins that tested positive on pathologic examination, of whom one was free of disease; one patient who underwent amputation died of disease. On presentation with regional metastasis (n = 12), only one of five patients who underwent wide local excision and one of seven patients who underwent amputation were free of disease. Primary amputation offered no apparent overall survival benefit to patients presenting with regional metastasis. The favorable outcome after local resections for localized disease indicates that wide local excision with margins that test negative on pathologic examination is preferable to radical amputation in these patients.

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Epithelioid sarcoma. An analysis of fifty-one cases.

Cited by 133 publications

References 0 publications

Prognostic Factors for Survival in Patients with Epithelioid Sarcoma: 441 Cases from the SEER Database

Prognostic Factors for Survival in Patients with Epithelioid Sarcoma: 441 Cases from the SEER Database

Orthopaedic Case of the Month: A 51-year-old Man with a Painless Wrist Mass

Extremity Epithelioid Sarcoma

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