Epithelioid osteoblastoma: A histopathological dilemma between juvenile ossifying fibroma and low-grade osteosarcoma

Prabhu, Sudeendra; Adyanthaya, Soniya; Jose, Maji; Rao, B H Sripathi

doi:10.4103/0973-029x.203772

Cited by 4 publications

(1 citation statement)

References 4 publications

(8 reference statements)

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“…The clinical and radiographic features of epithelioid osteoblastoma may also resemble juvenile ossifying fibroma, a fibro-osseous lesion that affects mostly children and young adults. 24 Microscopically, the presence of sheets of epithelioid osteoblasts and the absence of a highly cellular fibrous stroma, typical of juvenile ossifying fibroma, 25 supported the diagnosis of epithelioid osteoblastoma in our cases.…”

Section: Discussionsupporting

confidence: 70%

Clinicopathologic study of 6 cases of epithelioid osteoblastoma of the jaws with immunoexpression analysis of FOS and FOSB

Pereira

Andrade

Romañach

et al. 2020

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

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Section: Discussionsupporting

confidence: 70%

Clinicopathologic study of 6 cases of epithelioid osteoblastoma of the jaws with immunoexpression analysis of FOS and FOSB

Pereira

Andrade

Romañach

et al. 2020

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

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A case of epithelioid osteoblastoma of the thoracic vertebra in a 12-year-old male: a case report and review of literature

Zaresharifi,

Karimzadhagh,

Reihanian

et al. 2023

Annals of Medicine &Amp; Surgery

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Introduction and importance: Osteoblastoma (OB) is a rare benign bone tumor, representing less than 1% of all bone neoplasms. In contrast to the typical OB, a smaller subset known as “Epithelioid Osteoblastoma (EO)” exhibits a distinctive inclination for local invasion and recurrence. This rare variant can pose diagnostic challenges, particularly due to its unclear clinical and radiological presentation. Case presentation: This study details a clinical case of a 12-year-old boy experiencing pain from a lytic bone tumor located in the thoracic vertebrae (T3-T4), initially suggesting malignancy. Following extensive curettage, histopathological analysis confirmed the diagnosis of Epithelioid Osteoblastoma through immunohistochemical staining. Subsequent follow-up at three months revealed the absence of no pain or recurrence of the lesion. Clinical discussion: Distinguishing EO from a malignant tumor requires a multidisciplinary approach, considering clinical, radiographic, and histological features that differentiate the two entities. Conclusion: The goal of this case presentation is to increase awareness regarding this recurrent tumor variant, which poses diagnostic challenges, particularly in distinguishing it from malignant tumors, including osteosarcoma.

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A Case of Juvenile Psammomatoid Ossifying Fibroma on Skull Base

Kim

Lee

Choi

et al. 2018

Journal of Craniofacial Surgery

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Juvenile psammomatoid ossifying fibroma (JPOF) is a rare tumor that occurs in maxillary sinus or orbit. Complete removal is required due to the aggressive and locally destructive nature. It is hard to distinguish from psammomatoid meningioma in cranial lesion and to remove completely. The authors are presenting a case of 26-year-old male with JPOF on skull base and report this case with review of literature.

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Epithelioid osteoblastoma: A histopathological dilemma between juvenile ossifying fibroma and low-grade osteosarcoma

Cited by 4 publications

References 4 publications

Clinicopathologic study of 6 cases of epithelioid osteoblastoma of the jaws with immunoexpression analysis of FOS and FOSB

Clinicopathologic study of 6 cases of epithelioid osteoblastoma of the jaws with immunoexpression analysis of FOS and FOSB

A case of epithelioid osteoblastoma of the thoracic vertebra in a 12-year-old male: a case report and review of literature

A Case of Juvenile Psammomatoid Ossifying Fibroma on Skull Base

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