Epithelioid Hemangioendothelioma of the Phalanx: A Case Report

Metakarpta soliter epiteloid hemanjiyoendoteliyom

“…[7] The presence of Weibel-Palade bodies and positivity for endothelial markers such as CD31, CD34, factor VIII-related antigen and Ulex europaeus binding suggest that the tumor originates from vascular endothelium. [16,17] The treatment used for the patient presented here differs from that in previous reports of epithelioid hemangioendothelioma in hand bones. For their patient who had a metacarpal tumor, Tsuneyoshi et al [17] used curettage.…”

“…[6,[15][16][17] In the series by Tsuneyoshi et al, [17] multicentric tumors were common, occurring in nine of 14 patients, and in the study by Kleer et al [7] approximately half of the patients had multiple lesions. The major differences between this tumor's occurrence in the upper versus lower extremities is that it is rarer in the upper extremities, and that its clinical presentation can differ according to the anatomical structures involved.…”

“…[7,[16][17][18] In the series reported by Kleer et al, [7] periosteal reaction was rare and soft tissue extension occurred in approximately one-fourth of the patients. In our patient, extension of the tumor into soft tissue was apparent on MRIs (Figures 3a, b).…”

“…For their patient who had a metacarpal tumor, Tsuneyoshi et al [17] used curettage. For a patient with a solitary tumor of the phalanx, Kitagawa et al [16] used curettage and an autogenous bone graft from the iliac crest. Bruegel et al [14] described a patient who had tumors in the middle, ring and little fingers of the right hand.…”

“…[7] In the bones of the hand it is very rare, and to our knowledge it has been described in the metacarpal in only one patient previously, as part of multicentric disease. [7,[14][15][16][17] We describe here a female patient with a solitary epithelioid hemangioendothelioma of the second metacarpal, a condition that to our knowledge has not been previously reported.…”