Epithelioid angiosarcoma of the maxillary sinus and the maxilla: A case report and review of the literature

Sinonasal Tract Angiosarcoma: A Clinicopathologic and Immunophenotypic Study of 10 Cases with a Review of the Literature

“…Magnetic resonance imaging (MRI) shows the tumor to be bright on T2-weighted images. Angiography is an excellent modality to identify the extent of the tumor and show the feeder vessel(s) if they are present, while also allowing for pre-surgical angiographic embolization, if desired [19,22,29,30,34].…”

Stereotactic radiotherapy with CyberKnife for a large angiosarcoma of the maxillary sinus: A case report

“…Previous reports have demonstrated that overall prognosis of angiosarcomas is poor because they present as exceedingly aggressive neoplasms with a propensity for local recurrence and early distant metastasis, even when multimodality therapy in provided [4,9]. Indeed, only 20% of all patients with angiosarcomas are free of disease at 5 years [2,3], and the 5-year survival rate of angiosarcomas in the head and neck region is 10-35% [4,8]. Furthermore, it is especially difficult to achieve adequate surgical margins in the head and neck region because of anatomic factors [2].…”

“…The most common primary site of angiosarcoma is the head and neck region, accounting for more than 50% of angiosarcoma cases [2,4,5]. These lesions have a particular predilection for the superficial soft tissue of the scalp and face [2,3,5]. Yet, the paranasal sinus is an uncommon primary location for angiosarcomas, accounting for less than 0.1% of all paranasal sinus malignancies [8].…”

“…Previous reports have demonstrated that the overall prognosis of angiosarcoma is poor, with a 5-year disease-free survival rate of 10-35% [2][3][4][5]. Angiosarcoma has a poor prognosis because of its propensity for local recurrence and early distant metastasis, even when multimodal therapy is provided [2,5].…”

“…Angiosarcomas only account for approximately 1-2% of all soft tissue sarcomas [2][3][4][5], which can occur in any anatomical area [2,5]. Angiosarcomas frequently occur in the elderly population [4][5][6][7].…”