Epithelial Tumors

Franchi, Alessandro

doi:10.1007/978-3-030-29848-7_6

Cited by 2 publications

(1 citation statement)

References 178 publications

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“…The introduction of these diagnostic tests could explain the relative increase in the number of diagnosed cases. In fact, before its description, most cases were diagnosed as sinonasal undifferentiated carcinoma (SNUC) or poorly differentiated squamous cell carcinoma [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

Sinonasal NUT Carcinoma: Delayed Diagnosis Due to the COVID-19 Pandemic and a Review of the Literature

Crocetta

Botti

Fornaciari

et al. 2021

Head and Neck Pathol

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NUT carcinoma (NUT-C) is a relatively new malignancy that was recently listed in the 4th edition of the WHO Classification of Head and Neck Tumors in 2017. NUT carcinoma is a rare, aggressive, poorly differentiated carcinoma genetically defined by chromosomal rearrangement of the nuclear protein in testis (NUTM1) gene. The prognosis is extremely poor, with a mean survival < 1 year. Recent publications suggest a multimodality treatment approach. In the existing literature, only a few reports of sinonasal NUT-C have been reported. Sinonasal NUT-C is considered a very rare entity, but because of its recent inclusion as a head and neck malignancy, its true prevalence is unknown. We report the case of a 56-year-old woman with NUT-C of the sinonasal cavities. In the case reported, the coexistence of Coronavirus disease 2019 (COVID-19)-related nasal congestion delayed the diagnosis of NUT-C. Clinical presentation, diagnosis and treatment modalities are discussed together with a review of the literature.

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Section: Discussionmentioning

confidence: 99%