Epithelial-myoepithelial carcinoma in the base of the tongue: a case report

Kumai, Yoshihiko; Ogata, Noboru; Yumoto, Eiji

doi:10.1016/j.amjoto.2005.05.016

Cited by 26 publications

(35 citation statements)

References 12 publications

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“…The high signal intensity in T2-weighted images is consistent with low-grade malignant salivary gland tumors, although it is not specific to MEC; high-grade salivary gland malignant tumors are reported to show a low signal intensity in T2-weighted images [9,13]. The tumor is enhanced by contrast media with various patterns, either slightly, well, or heterogeneously [3,8,9,13,17,18,21]. Contrast enhancement suggested a physiologically rich blood supply for the tumor, or highly vascularized characteristics of MEC [9].…”

Section: Discussionmentioning

confidence: 85%

“…Immunohistochemical examination with specific myoepithelial markers is helpful for diagnosis; i.e., diagnosis of MEC is established by cytokeratin activity and at least one of the other myoepithelial markers, including smooth muscle actin, glial fibrillary acidic protein, CD-10, calponin, and smooth muscle myosin heavy chain [1,2,11,16,18,19,23]. Our patient was positive for cytokeratin, smooth muscle actin, and Vimentin, and the diagnosis was compatible with MEC.…”

Section: Discussionmentioning

confidence: 88%

“…Few studies have examined the image features of MEC [3,[5][6][7][8][9][12][13][14][15][16][17][18][19][20][21][22][23], with most reports presenting well-defined, sometimes poorly-defined, and heterogeneous enhanced tumors in computed tomography (CT) and magnetic resonance (MR) images. In tumors involving the bone, bone destruction is often observed [5,6,15].…”

Section: Introductionmentioning

confidence: 99%

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Imaging features of myoepithelial carcinoma of the mandible with lymph node metastasis

et al. 2009

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Objectives To demonstrate the imaging characteristics of a patient with myoepithelial carcinoma (MEC) of the mandible accompanied by submandibular lymph node metastases, and to discuss the differential image-based diagnoses. Patients and resultsThe patient was a 57-year-old woman who had suffered from a dull pain in her left lower molar region for 3 months and had an elastic-soft mass in her submandibular region for 2 months. Computed tomography (CT) images showed permeative destruction of the bone trabecula and intermittent absorption of the cortical plates in the left mandible. The bone marrow of this area showed low signal intensity in a T1-weighted magnetic resonance (MR) image, slightly low signal intensity in a T2-weighted image, and marked contrast enhancement. A tumor was confirmed outside the buccal and lingual cortical plates. The left submandibular mass was shown as a well-defined, water-density mass by CT, low signal intensity in the T1-weighted MR image, and markedly high signal intensity in the T2-weighted image. The histopathological diagnosis was MEC of the mandible with submandibular lymph node metastasis. ConclusionsWe demonstrated the imaging characteristics of MEC, showing permeative destruction of the bone trabecula, intermittent absorption of the mandible, and cystic degeneration of the metastatic cervical lymph node.

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Section: Discussionmentioning

confidence: 85%

Section: Discussionmentioning

confidence: 88%

Section: Introductionmentioning

confidence: 99%

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Imaging features of myoepithelial carcinoma of the mandible with lymph node metastasis

et al. 2009

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“…Typically, the EMC is a low-grade malignancy and occurs mainly in the parotid gland [ 17 ], although it is described in mucoserous glands of the tongue [ 31 ], buccal mucosa [ 65 ], sinonasal tract [ 49 ] and low aerodigestive tract as well [ 12 , 19 , 40 , 44 ].…”

Section: Epithelial-myoepithelial Carcinomamentioning

confidence: 99%

Myoepithelial Carcinoma and Epithelial-Myoepithelial Carcinoma

Hellquist

Skálová

2014

Histopathology of the Salivary Glands

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“…Donath et al [2] in 1972 introduced the term EMC by noting the myoepithelial component as an integral part of the tumor. EMC occurs mainly in the parotid gland, but it has been also described in the submandibular gland, in the minor salivary glands and extra oral areas [3][4][5][6]. It is more commonly seen in females, with a peak incidence in the seventh decade [7].…”

Section: Introductionmentioning

confidence: 99%