Epithelial downgrowth after clear cornea phacoemulsification

Vargas, Luis G.; Vroman, David T; Solomon, Kerry D.; Holzer, MP; Escobar-Gómez, Marcela; Schmidbauer, Josef M.; Apple, David J.

doi:10.1016/s0161-6420(02)01274-5

Cited by 70 publications

(52 citation statements)

References 23 publications

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“…1 Typical clinical signs are decreased vision, mild inflammation, and a white or transparent membrane-like layer on the posterior surface of the cornea. At the end stage, the eye may become severely inflamed and can be painful secondary to glaucoma.…”

Section: Discussionmentioning

confidence: 99%

“…Small wounds make the procedure safer, with decreased trauma to the ocular structures, lower induced astigmatism, less surgical time, and fewer complications. 1 Downgrowth of epithelial cells into the anterior chamber is a rare complication of intraocular surgery. It occurs more readily when there is prolonged communication between the corneal epithelium and the anterior chamber, as in cases complicated by wound fistulas, 2 iris incarceration, 3 or vitreous in the wound, 3 highlighting the importance of appropriate wound architecture and prompt repair of a leaking wound.…”

Section: Jcrs Online Case Reports 2015; 3:49-52 Q 2015 Ascrs and Escrsmentioning

confidence: 99%

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Managing epithelial downgrowth after clear corneal phacoemulsification

Oliveira

Bordón

Mori

et al. 2015

Journal of Cataract and Refractive Surgery Online Case Reports

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We present a case in which epithelial downgrowth developed after uneventful clear corneal phacoemulsification. The diagnosis of epithelial downgrowth was confirmed by clinical features and anterior segment optical coherence tomography (OCT), high-frequency ultrasound (US), and confocal microscopy. Intracameral 5-fluorouracil (5-FU) was administered 3 times to control epithelial growth. Sixteen months after the last intervention, the epithelial layer did not appear to have increased. Although 5-FU seemed to be effective in preventing epithelial growth, we cannot be sure epithelial cell growth will not progress over time. Corneal melting is a potential complication of this treatment. Anterior segment OCT and high-frequency US were helpful tools in the diagnosis of epithelial downgrowth after clear corneal phacoemulsification.

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Section: Discussionmentioning

confidence: 99%

Section: Jcrs Online Case Reports 2015; 3:49-52 Q 2015 Ascrs and Escrsmentioning

confidence: 99%

Managing epithelial downgrowth after clear corneal phacoemulsification

Oliveira

Bordón

Mori

et al. 2015

Journal of Cataract and Refractive Surgery Online Case Reports

View full text Add to dashboard Cite

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“…Prognosis mostly depends on the type of downgrowth. 1 Epithelial cyst is quite different from the sheet-like forms of epithelial downgrowth. With well-defined borders, it is easier to diagnose cysts leading to earlier and more successful treatment by complete excision.…”

Section: Discussionmentioning

confidence: 99%

“…Thus, with sutureless phacoemulsification techniques, epithelial downgrowth has gradually found to be a much more rare complication after cataract surgery. 1 However, cases of epithelial downgrowth have been reported after a clear corneal phacoemulsification. [1][2][3][4][5] Herein, we describe a patient with advanced epithelial downgrowth seen after 2.5 years of a clear corneal phacoemulsification.…”

Section: Introductionmentioning

confidence: 99%

“…1 However, cases of epithelial downgrowth have been reported after a clear corneal phacoemulsification. [1][2][3][4][5] Herein, we describe a patient with advanced epithelial downgrowth seen after 2.5 years of a clear corneal phacoemulsification. This case report illustrated the use of anterior segment optical coherence tomography (ASOCT) to assess the relationship of epithelial membrane with anterior chamber structures.…”

Section: Introductionmentioning

confidence: 99%

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Epitelyal İçe Büyümenin Ön Segment Optik Koherens Tomografi Kullanılarak Değerlendirilmesi: Olgu Sunumu

Bozkurt¹,

Güneş²,

Bayramlar³

et al. 2013

tjo

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Epithelial downgrowth is a rare, sight-threatening complication which can develop following anterior segment surgeries with corneal incisions. However, due to translucent nature of epithelial membrane and diversity of clinical signs, epithelial downgrowth usually goes undiagnosed until its late stages. Use of anterior segment imaging techniques may be utilized to ease the diagnosis of cases with clinical suspicion of epithelial downgrowth. An 83-year-old male patient with a history of cataract surgery three years ago was clinically diagnosed as epithelial downgrowth, and argon laser photocoagulation was applied on the iris to confirm clinical suspect, but no bleaching was seen on the iris. Later on, anterior segment optical coherence tomography was performed to visualize the epithelial membrane and its relationship with anterior segment structures. Anterior segment optical coherence tomography was found to be useful for supporting the clinical suspicion in this case which could not be confirmed by argon laser application. (Turk J Ophthalmol 2013; 43: 474-6) Key Words: Epithelial downgrowth, cataract surgery complications, anterior segment optical coherence tomography ÖzetEpitelyal içe büyüme, kornea kesilerinden uygulanan ön segment cerrahilerinden sonra izlenebilen, ender rastlanan, görmeyi tehdit eden bir komplikasyondur. Ancak, epitelyal membranın yarı saydam olması ve klinik bulguların çeşitliliğinden dolayı, epitelyal içe büyüme tanısı genellikle hastalığın geç evrelerine kadar konulamaz. Ön segment görüntüleme teknikleri, klinik olarak epitelyal içe büyüme şüphesi mevcut vakalarda teşhisi kolaylaştırmak amacıyla kullanılabilir. Üç yıl önce katarakt cerrahisi geçirme hikayesi mevcut olan seksen üç yaşında erkek hastanın sağ gözüne klinik olarak epitelyal içe büyüme teşhisini kondu ve klinik şüpheyi doğrulamak amacıyla iris üzerine argon laser fotokoagülasyon uygulandı, fakat iris üzerinde beyazlama izlenmedi. Sonrasında ön segment optik koherens tomografisi, epitelyal membranı ve epitelyal membranın ön segment yapıları ile ilişkisini görüntülemek için kullanıldı. Argon laser uygulaması ile doğrulanamayan bu olguda, ön segment optik koherens tomografi, klinik şüphenin desteklenmesi açısından yararlı bulunmuştur. (Turk J Ophthalmol 2013; 43: 474-6) Anah tar Ke li me ler: Epitelyal içe büyüme, katarakt cerrahisi komplikasyonlari, ön segment optik koherens tomografi

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