Epistaxis and hypertension

Charles, Roger; Corrigan, Elizabeth

doi:10.1136/pgmj.53.619.260

Cited by 26 publications

(15 citation statements)

References 4 publications

(4 reference statements)

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“…In 1959, Mitchell [7] statistically compared two groups of patients (one group of 374 patients with a history of hypertension and another group of 162 patients with acute epistaxis but with no history of hypertension) and concluded that, in the absence of local nasal disease, epistaxis was associated with high BP. In 1977, Charles and Corrigan [8] confirmed this conclusion in a series of 194 patients and, more recently, Isezuo et al [9] also showed a statistically significant association between epistaxis and hypertension in a series of 62 patients. However, Fuchs et al [10] in a sample of 1,174 subjects over the age of 18 years representative of Porto Allegre general population, found no association between epistaxis and hypertension.…”

Section: Association Between Epistaxis and Hypertensionsupporting

confidence: 50%

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Serious spontaneous epistaxis and hypertension in hospitalized patients

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Biet

Liabeuf

et al. 2011

Eur Arch Otorhinolaryngol

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The aim of the study was to evaluate the role of hypertension in patients hospitalized for serious spontaneous epistaxis. This 6-year retrospective study was based on 219 patients hospitalized in a University Hospital ENT and Head and Neck surgery department for serious spontaneous epistaxis. The following parameters were recorded: length of hospital stay, history of hypertension, blood pressure (BP) recordings (on admission, during hospitalization and on discharge), epistaxis severity criteria, including medical and/or surgical management of epistaxis (blood transfusion depending on blood count, embolization, surgery), medications affecting clotting. Epistaxis was classified into two groups: serious and severe. No significant differences were observed between the two groups in terms of age, sex ratio, history of epistaxis and BP characteristics including history of hypertension, mean BP on admission, mean arterial pressure on discharge and number of patients in whom BP was difficult to control. Patients with more severe epistaxis had a similar exposure to anticoagulant and platelet antiaggregant medications as patients with less severe epistaxis. Overall, on univariate logistic regression analysis, no factors were independently associated with severity of epistaxis. The pathophysiology of serious spontaneous epistaxis remains to be unclear. It concerns elderly patients (>60-70 years old) with a history of hypertension in about 50% of cases. Serious spontaneous epistaxis may also be the presenting sign of underlying true hypertension in about 43% of patients with no history of hypertension. However, hypertension per se does not appear to be a statistically significant causal factor and/or a factor of severity of serious spontaneous epistaxis.

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Section: Association Between Epistaxis and Hypertensionsupporting

confidence: 50%

“…Hypertension has been considered to be a major cause of spontaneous epistaxis for a long time [7,8]. However, particularly in the recent medical literature, the relationship between hypertension and epistaxis appears to be more controversial [9][10][11][12][13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Serious spontaneous epistaxis and hypertension in hospitalized patients

Page

Biet

Liabeuf

et al. 2011

Eur Arch Otorhinolaryngol

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“…To our knowledge, our observation is unique in describing the association between enlarged vessels observed at rhinoscopy and epistaxis in patients with hypertension examined far from the acute episode of epistaxis. Mitchell 10 and Charles and Corrigan 11 analyzed the association of epistaxis and hypertension in patients classified by the presence of nonspecified nasal abnormalities, but did not discriminate if the frequency of epistaxis was more common in the presence of those abnormalities.…”

Section: Discussionmentioning

confidence: 99%

Is Epistaxis Evidence of End‐Organ Damage in Patients With Hypertension?

Fuchs

Facco

et al. 1999

The Laryngoscope

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A definite association between blood pressure and history of adult epistaxis in hypertensive patients was not found. The evidence for an association of duration of hypertension and left ventricular hypertrophy with epistaxis suggests that epistaxis might be a consequence of long-lasting hypertension. The association between the presence of enlarged vessels at rhinoscopy with history of epistaxis in hypertensive patients is a novel observation that needs to be addressed in future observations.

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“…Varshney and Saxena,7 in India recorded HTN as second commonest cause of epistaxis followed by idiopathic causes and also study by Charles R in Bristol General Hospital. 21 So this study also emphasizes on the regular blood pressure check and compliance to antihypertensive medications.…”

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confidence: 99%