Episodic memory in normal and pathological aging at the RAVLT Test: Comparisons of immediate and delayed recall.

Abstract

Objective: The present study investigates the difference between trials A6 and A7 of the Rey Auditory-Verbal Learning Test (RAVLT) test in three different groups of older adults-normal cognition (Controls), mild cognitive impairment (MCI), and Alzheimer's Dementia (AD). Method: The study comprises 180 subjects 60 years old or more. We compared scores in trials 6 and 7 of list A (A6 and A7) using the Wilcoxon signed ranks test. Subsequently, we computed its difference (A6-A7) and used Mann-Whitney to analyze which groups' differences were more relevant. Results: Comparison analysis showed a significant difference between A6 and A7 trial performance only in the AD group ( p < .01). When we compared these differences between groups, the only significant difference occurred between controls and AD ( p < .01). Conclusions: There is a significant difference in RAVLT trials A6 and A7 in the AD group, but this difference does not appear in the control and the MCI groups. The differences between A6 and A7 trials of RAVLT are restricted to comparing Controls × AD patients. Our study corroborates the instrument's effectiveness for the diagnosis of Alzheimer's dementia.

Episodic Memory in Amnestic Mild Cognitive Impairment (aMCI) and Alzheimer’s Disease Dementia (ADD): Using the “Doors and People” Tool to Differentiate between Early aMCI—Late aMCI—Mild ADD Diagnostic Groups

“…Episodic memory tasks, such as RAVLT and Rey–Osterrieth complex figure test (ROCFT), can predict the progression from aMCI to dementia with high levels of sensitivity [ 19 ]. The accuracy of these findings are confirmed with single-photon emission computed tomography (SPECT) data showing alterations in brain connectivity and cerebral blood flow, especially in the medial temporal lobe, and hypoperfusion in the posterior cingulate cortex [ 19 , 20 ]. Mascoso et al (2019) examined 387 MCI amyloid-positive patients, cognitively staged as early or late based on episodic memory performance.…”