Epiretinal membrane surgery: Anatomic and functional outcomes

García-Fernández, María; Navarro, Joaquín Castro; Castaño, C. González; Alonso, Ana; Gil, M. Fonollá

doi:10.1016/j.oftale.2012.07.003

Cited by 11 publications

(5 citation statements)

References 17 publications

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“…The postoperative structural OCT evaluation often shows a gradual re-establishment of foveal profile and partial reconfiguration of retinal layers similar to the one prior to distortion. 27,28 In accordance with the literature, 26–29 in our cohort the macular thickness decreased after surgery both in terms of foveal thickness (t test, p-value < 0.001) and macular volume (t test, p < 0.001).…”

Section: Discussionsupporting

confidence: 91%

Correlation between retinal sensitivity and retinal vascular perfusion after idiopathic epiretinal membrane peeling

Nicolai,

Franceschi,

De Turris

et al. 2023

European Journal of Ophthalmology

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Background To evaluate the correlations between anatomical and functional changes after idiopathic epiretinal membrane (iERM) surgery. Methods In this prospective, observational, single-center study, consecutive patients who underwent iERM peeling were enrolled. Reported data were pre- and postoperative best-corrected visual acuity (BCVA), retinal sensitivity (RS) and fixation stability values on microperimetry, structural macular features on SD-OCT and OCTA. RS of foveal and parafoveal area was analysed and two sub-groups were identified whether RS improved or remained unchanged/worsened after surgery; consequently, vascular perfusion density (VPD) of the same area was studied. Results Twenty-nine eyes of 29 patients were examined. The post-operative improvement in terms of BCVA, RS and fixation within the central 4 degrees was significant (p < 0.001, p < 0.001, p = 0.001), as well as the foveal thickness and macular volume change/reduction (p < 0.001). The pre-operative superficial VPD, choriocapillaris VPD and capillary free zone (CFZ) area were significantly reduced compared to the fellow healthy eye (p = 0.001, p = 0.02, p < 0.001). Choriocapillaris VPD showed a statistically significant increase after surgery (p < 0.02). Superficial, deep and choriocapillaris VPD of the improved RS group showed a significant increase both in foveal (p = 0.03, p = 0.03, p = 0.01) and parafoveal areas (p = 0.01, p = 0.03, p = 0.001). Conclusions We reported a higher VPD in the retinal area that experienced a retinal sensitivity improvement 6 months after ERM surgery. This result objectifies the tight bond between visual function and retinal perfusion in ERM patients.

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Section: Discussionsupporting

confidence: 91%

Correlation between retinal sensitivity and retinal vascular perfusion after idiopathic epiretinal membrane peeling

Nicolai,

Franceschi,

De Turris

et al. 2023

European Journal of Ophthalmology

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“…We presume also that the decrease of visual acuity could be secondary to folded layers of inhomogeneous soft fibrous material (cases 1, 3, 6, and 14), not necessarily very consistent, which bend the inner retina. The improvement of visual acuity after surgery takes months, as already described (29)(30)(31), and in our case series gained visual acuities after surgery were found also after peeling of soft splay tissue. The surgeon must remove all tissue adherents to the retina.…”

Section: Discussionsupporting

confidence: 86%

Multilayer Microstructure of Idiopathic Epiretinal Macular Membranes

Azzolini

Congiu

Donati

et al. 2017

European Journal of Ophthalmology

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“…However, visual recovery may take several months to as long as 1 year as the retinal morphology normalizes slowly [8, 18]. However, persistent residual intraretinal edema is sometimes still present, limiting the possibility of a complete visual function recovery [6, 7]. To date, the mechanism of macular edema in idiopathic ERM has not been fully studied.…”

Section: Discussionmentioning

confidence: 99%

“…Surgical removal of the membrane in patients with significant symptoms can improve visual acuity and reduce metamorphopsia in approximately 70% of cases [3–5]. However, persistent residual intraretinal edema is sometimes still present, limiting the possibilities of complete visual function recovery [6, 7]. From our previous study, stable vision is usually achieved approximately 9 months after PPV, and intravitreal injection of bevacizumab cannot further improve the final visual and anatomical outcome [8].…”

Section: Introductionmentioning

confidence: 99%

Dexamethasone Intravitreal Implant (Ozurdex) for Long-Term Macular Edema after Epiretinal Membrane Peeling Surgery

Chang

Liu

Kao

et al. 2018

Journal of Ophthalmology

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Purpose To investigate the functional and anatomical outcome of the 0.7 mg dexamethasone (Ozurdex) intravitreal implant (IVD) in eyes with long-term macular edema after macular epiretinal membrane removal. Methods We enrolled 40 eyes with persistent macular edema at least 12 months after epiretinal membrane removal. Twenty eyes in the IVD group received IVD and the other 20 eyes were in the control group. The main outcome measures were change in best-corrected visual acuity (BCVA) and central foveal thickness (CFT). Results For eyes in the IVD group, the mean BCVA improved by 3.45 lines to 0.47 logMAR one month after IVD. However, the mean BCVA improved by only 0.14 lines to 0.74 logMAR at the same time in eyes in the control group. Six months later, the mean BCVA improved to 0.31 and 0.74 logMAR in the IVD and control groups, respectively. In the IVD group, the mean CFT decreased rapidly by 116.8 μm to 333.9 μm one month after IVD. Thereafter the CFT decreased at a slower pace. In the control group, the CFT remained static during the follow-up period. However, in the IVD group, 6 months after IVD, the CFT seemed to have a tendency to increase. Conclusions Single IVD could significantly decrease macular edema and improve visual outcome for eyes with persistent long-term macular edema after macular ERM removal and the effect can be sustained as long as 6 months after the initial injection. However, in order to maintain the visual and anatomical outcome, repeat IVD might be considered if macular edema recurs.

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Epiretinal membrane surgery: Anatomic and functional outcomes

Cited by 11 publications

References 17 publications

Correlation between retinal sensitivity and retinal vascular perfusion after idiopathic epiretinal membrane peeling

Correlation between retinal sensitivity and retinal vascular perfusion after idiopathic epiretinal membrane peeling

Multilayer Microstructure of Idiopathic Epiretinal Macular Membranes

Dexamethasone Intravitreal Implant (Ozurdex) for Long-Term Macular Edema after Epiretinal Membrane Peeling Surgery

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