Epipericardial Fat Necrosis: A Unique Clinicoradiologic Disease

Fred, Herbert L.

doi:10.1080/08998280.2016.11929503

Cited by 1 publication

(11 citation statements)

References 14 publications

(19 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recommendations for treatment and follow-up include a shorter period of nonsteroidal anti-inflammatory drugs (NSAIDs) 3 , 10 , 14 , 20 and a follow-up CT scan in 4 to 8 weeks to confirm healing and definitely exclude malignancies. 3 , 9 Most patients are pain free within the first week 1 , 14 , 17 , 21 and serial CT has shown partial or full resolution after 2 to 12 weeks. 8 , 9 , 11 , 22 , 23 Relapses are sometimes seen, 17 , 19 , 21 , 22 but reports of these are rare and prognosis is usually very good.…”

Section: Discussionmentioning

confidence: 99%

“…Surgery may still be indicated in rare cases if diagnostic uncertainties remain or for treatment of persisting, intractable pain. 1 , 13 , 17 , 20 …”

Section: Discussionmentioning

confidence: 99%

“… 11 , 13 , 21 The latter have been seen in some patients undergoing surgery. 1 , 16 , 20 Obesity will generally increase the volume of epipericardial fat and was originally suggested as a predisposing factor for EFN. So far, no clear correlation has been observed and the theory is weakened.…”

Section: Discussionmentioning

confidence: 99%

“…Recent literature most often refers to the condition as epipericardial fat necrosis (EFN), but it is also known as pericardial fat necrosis and mediastinal fat necrosis. 1 …”

Section: Introductionmentioning

confidence: 99%

“… 1 , 2 Today’s understanding of EFN is mostly based on clinical reports containing a single or a limited number of cases. A comprehensive search in English-language medical literature from 2016 yielded only 57 reported cases since the first one in 1957, 1 and to our knowledge, the only prevalence-estimate is based on 2 retrospective studies from Brazil demonstrating a prevalence of approximately 2% in patients admitted to the emergency department (ED) with acute atypical chest pain. 3 , 4 Later, the same authors found an increase in presumed EFN diagnosis in their own clinic after disseminating knowledge of the condition and encouraging their radiologists to look for the features of EFN in chest computed tomography (CT) scans taken in the setting of pleuritic chest pain.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Epipericardial Fat Necrosis: A Case Report and a Review of the Literature

Mortensen

Lappegård

2020

Clin Med Insights Case Rep

View full text Add to dashboard Cite

Epipericardial fat necrosis (EFN), also known as pericardial or mediastinal fat necrosis, has until lately been considered an unusual cause of acute chest pain. Due to increased use of computed tomography (CT) and other imaging techniques, EFN is now believed to be an under-diagnosed cause of acute chest pain. We here present a patient with a short history of acute, left-sided pleuritic chest pain and dyspnoea, with total resolution of symptoms upon few days with nonsteroidal anti-inflammatory drugs (NSAIDs) treatment. Chest X-ray showed a paracardial opacity with ipsilateral pleural effusion, echocardiography revealed features of EFN, and CT scan demonstrated the cardinal lesion of EFN—an ovoid, fat-containing paracardial mass with surrounding inflammatory stranding. There was a near to full radiological resolution in 3 weeks.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Surgery may still be indicated in rare cases if diagnostic uncertainties remain or for treatment of persisting, intractable pain. 1 , 13 , 17 , 20 …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Recent literature most often refers to the condition as epipericardial fat necrosis (EFN), but it is also known as pericardial fat necrosis and mediastinal fat necrosis. 1 …”

Section: Introductionmentioning

confidence: 99%