Epipalpebral conjunctival chondroid choristoma: Interesting developmental anomaly presenting in an adult

Ojha, Pushpanjali R; Deshpande, Archana; Gargade, Chitrawati Bal; Nigam, Jitendra Singh

doi:10.4103/ijo.ijo_39_17

Cited by 5 publications

(1 citation statement)

References 9 publications

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“…2 Ojha et al described a patient who presented with a nodular pedunculated polypoidal mass on the palpebral conjunctiva that was clinically diagnosed as chalazion but was diagnosed histologically as a cartilaginous choristoma. 10 In our case, histopathological examination was required to confirm the diagnosis of a cartilaginous choristoma, which presented atypically, highlighting the importance of thorough tissue examination.…”

Section: Discussionmentioning

confidence: 83%

Epibulbar simple cartilaginous choristoma associated with unique pigmented multicystic component

Yu,

Eagle,

Syed

2024

European Journal of Ophthalmology

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Purpose To report an atypical presentation of an epibulbar simple cartilaginous choristoma with a unique pigmented multicystic component. Case Description A 69-year-old African American female presented for evaluation of a right nasal epibulbar lesion that had progressed over the prior year. Slit-lamp evaluation revealed an immobile, mildly pigmented multicystic lesion measuring 6.0 × 4.5 mm that involved the nasal bulbar conjunctiva and the plica semilunaris. The lesion appeared benign, without feeder vessels or features of epithelial dysplasia. Given its recent growth and the patient's cosmetic concerns, the lesion was excised with ocular surface reconstruction. Histopathological evaluation disclosed a well-circumscribed nodule of well-differentiated cartilage in the substantia propria, consistent with a simple cartilaginous choristoma. The overlying conjunctival stroma contained multiple cysts lined by focally pigment epithelium. The patient recovered well from surgery, with satisfactory cosmetic results. Conclusions Our case of epibulbar simple cartilaginous choristoma includes a prominent superficial component of pigmented epithelial cysts, which has not been previously reported in the literature. This augments our knowledge on the spectrum of presentations of cartilaginous choristomas and underscores the importance of histopathological evaluation for definitive diagnosis.

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Section: Discussionmentioning

confidence: 83%

Epibulbar simple cartilaginous choristoma associated with unique pigmented multicystic component

Yu,

Eagle,

Syed

2024

European Journal of Ophthalmology

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Bilateral Chondroid Metaplasia of Conjunctiva Associated With Monoclonal Gammopathy of Undetermined Significance

Mancera

Whitfield

Margo

et al. 2020

Cornea

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Purpose: To describe a case of a patient with bilateral proliferation of chondrocytes of the lower palpebral conjunctiva. Methods: Observational case report and review of relevant literature. Results: Conjunctival biopsy from an 83-year-old man with bilateral acquired lower conjunctival nodules revealed a benign proliferation of chondrocytes. A general medical evaluation revealed serum monoclonal gammopathy with light-chain proteinuria. Conclusions: Bilateral-acquired benign chondrocyte tumefactions of the palpebral conjunctiva have not been previously reported. This initiated a search for a biologically plausible explanation. The findings in this report support that these proliferations represent chondroid metaplasia related to light-chain deposition. The diagnosis requires exclusion of other forms of chondrocyte proliferation including well-differentiated chondrosarcoma.

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Epibulbar complex cartilaginous choristoma

et al. 2018

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To newly describe the clinical and histopathological characteristics of epibulbar complex cartilaginous choristoma incidentally observed in a series of pterygium excision patients.Noncomparative case series with chart review of 8 patients.During a 4-year period, we identified 8 cases of conventional unilateral nasal subpterygial cartilaginous choristoma in 1799 pterygium patients and analyzed their clinicopathological features. The incidence rate of this entity is 0.44% in pterygium patients. All of the cartilaginous choristomas were buried deep in the caruncle, covered by the pterygium, and embedded in tenon facia tissue. Its clinicopathological characteristics include hyaline cartilaginous tissue that is surrounded by fibrous connective tissue and smooth muscle bundles. S-100 protein-staining specifically revealed chondrocytes embedded within chondroid matrix.Epibulbar complex cartilaginous choristoma covered by pterygia and predominantly observed in the older population is rare. The lesions were buried deep in the caruncle, covered by the pterygium and embedded in tenon fascia tissue. These findings are inconsistent with those in previous reports.

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Epipalpebral conjunctival chondroid choristoma: Interesting developmental anomaly presenting in an adult

Cited by 5 publications

References 9 publications

Epibulbar simple cartilaginous choristoma associated with unique pigmented multicystic component

Epibulbar simple cartilaginous choristoma associated with unique pigmented multicystic component

Bilateral Chondroid Metaplasia of Conjunctiva Associated With Monoclonal Gammopathy of Undetermined Significance

Epibulbar complex cartilaginous choristoma

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