Epimyoepithelial carcinoma - an uncommon salivary gland tumour

Epithelial-myoepithelial carcinoma of floor of mouth: A case report with cytological, histological and immunohistochemical correlation

“…In the presenting case, the tumor could have been a primary onset EMC or an EMC-ex-PA. There have been cases of recurrence of tumor by simple excision alone,[ 1 3 7 ] hence we chose wider margins of healthy mucosa. The prognosis of EMC is fairly good as the median disease free survival rate is reported to be 11.34 years.…”

Proper management of suspicious actinic cheilitis

“…EC is a very rare tumor in the SGs and is present in less than 1.1% of all epithelial SG neoplasia [3–5]. Most ECs have been known to be involved in major SGs including the parotid gland and do not often occur in minor SGs such as the lip mucosa.…”

“…3). The differential diagnosis of EC composed of predominantly clear cells includes actinic cell adenocarcinoma, mucoepidermoid carcinoma, oncocytoma, and clear cell adenocarcinoma of MSGs [3–5]. There are no definite treatment guidelines for EC in the lips, but surgical excision with a wide resection margin could be recommended in cases involving major SG.…”

“…Epimyoepithelial carcinoma (EC), previously called epithelial myoepithelial carcinoma (EMC), is a very rare salivary gland (SG) neoplasm that has classical biphasic histologic findings of small tubules and glandular lumina surrounded by clear myoepithelial cells. This uncommon low-grade neoplasm accounts for 1–2% of SG tumors arising in the intercalated ducts, is most commonly found in the parotid gland at more than 85% incidence, and has female preference with the peak age of 60 to 70 years [3, 4].…”