Epileptiform Electroencephalogram during Mask Induction of Anesthesia with Sevoflurane 

Abstract

Sevoflurane mask induction elicits epileptiform EEG patterns. These are associated with an increase in heart rate in patients with controlled hyperventilation and also during spontaneous breathing of sevoflurane.

Emergence delirium in children

“…The halogenated anaesthetics sevoflurane, isoflurane and desflurane are thought to play an important role by altering the child's brain activity and upsetting the balance between central nervous system neuronal synaptic excitation and inhibition [5]. The incidence varies depending on the diagnostic criteria used, and although it is considered to occur with a relatively high frequency in children following sevoflurane anaesthesia, a recent review by Costi et al [6] found no difference in the incidence of emergence delirium following sevoflurane, desflurane or isoflurane.…”

Epilepsietypische EEG-Aktivität: Auftreten bei Sevoflurananflutung und nicht unter Propofolapplikation

“…Kinder mit epilepsietypischen Potenzialen im EEG unter Sevofluran publiziert wurden [5,17], gab es kürzlich mehrere Berichte über das Auftreten von epilepsietypischer Aktivität bei Erwachsenen mit und ohne Epilepsieanamnese, bei denen Sevofluran verwendet wurde [4,10,11,15,18]. Im Folgenden möchten wir über eine Patientin berichten, die sowohl eine Propofol-als auch, bei einem weiteren Eingriff, eine Sevoflurannarkose erhielt.…”

Inhalation induction with sevoflurane for electroconvulsive therapy: a case series

“…It is non-irritant, has a pleasant ethereal smell, and, with its low blood gas solubility of 0.6, induces anaesthesia rapidly. It also appears to have excitatory effect on the electroencephalogram (EEG) during inhalational induction (Yli-Hankala et al, 1999;Sato et al, 2002). It would appear to be a suitable agent for repeated induction of anaesthesia for short procedures, including ECT.…”

“…The effect of sevoflurane on the electrophysiology of the brain has been studied, with conflicting results. Several workers have recorded epileptiform EEG tracings accompanied in some cases by visible motor manifestations (Yli-Hankala et al, 1999;Sato et al, 2002). The ability of sevoflurane to modulate neuroexcitability was shown in one study on patients with epilepsy to be dose-dependent, manifested most at near burst suppression doses of 1.5 minimum alveolar concentration (MAC).…”