Epileptic seizure in primary intracranial sarcoma: a case report and literature review

Chen, Yen Ping; Lee, Hsiu Fen; Wong, Tai-Tong

doi:10.1007/s00381-016-3174-3

Cited by 4 publications

(6 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…18 Primary CNS sarcomas account for 0.1%-4.3% of all sarcomas. 19 These tumors are thought to originate from pluripotent primitive mesenchymal cells in the leptomeninges. Sarcomas may arise within extensions of leptomeningeal tissue into the brain or spinal cord via the pia mater, the periadventitial spaces, or the choroid plexus.…”

Section: High-grade Spindle Cell Sarcoma Nosmentioning

confidence: 99%

“…20 While the pathogenesis of CNS sarcoma is not completely understood, postulated risk factors include radiation exposure, history of head trauma, chemical exposure, viral infections, and genetics. 19 A wide variety of histological subtypes, including malignant fibrous histiocytoma, chondrosarcoma, rhabdomyosarcoma, liposarcoma, fibrosarcoma, angiosarcoma, leiomyosarcoma, and epithelioid sarcoma, have been reported. 21 Neuroimaging findings are typically nonspecific, and these lesions are usually described as rapidly growing heterogeneous tumors with cystic, solid, or complex components.…”

Section: High-grade Spindle Cell Sarcoma Nosmentioning

confidence: 99%

“…21 Neuroimaging findings are typically nonspecific, and these lesions are usually described as rapidly growing heterogeneous tumors with cystic, solid, or complex components. 19 When a malignant spindle cell neoplasm shows highgrade pathological features with numerous mitoses, and investigation with immunohistochemical and molecular 18,19 1 case was in the posterior fossa. These cases are described in Table 2 as examples of the clinical findings that may occur with this tumor.…”

Section: High-grade Spindle Cell Sarcoma Nosmentioning

confidence: 99%

“…In particular, leptomeningeal spread at the time of diagnosis is a poor prognostic sign. 18,19,22 Management of any intracranial sarcoma requires a multimodal approach, including resection, radiotherapy, and chemotherapy. Predictably, total resection increases mean survival time compared with subtotal resection.…”

Section: High-grade Spindle Cell Sarcoma Nosmentioning

confidence: 99%

See 3 more Smart Citations

Malignant spindle cell tumors of the posterior fossa in children: case series and review of management

Gigliotti

Mau

Specht

et al. 2021

Journal of Neurosurgery: Pediatrics

View full text Add to dashboard Cite

OBJECTIVE The WHO Classification of Tumours of the Central Nervous System (2016) classifies nonmeningothelial malignant spindle cell tumors involving the extraaxial tissues of the posterior fossa as melanocytic tumors and malignant mesenchymal tumors (sarcomas). The objective of this study was to conduct a review of the literature pertaining to the management strategies of posterior fossa malignant spindle cell tumors in the pediatric population. METHODS The authors performed an institutional search of their pathology database for patients younger than 18 years of age who presented with posterior fossa malignant spindle cell tumors. A literature review was also performed using the PubMed database, with “posterior fossa” or “spindle cell tumors” or “Ewing sarcoma” or “high-grade” or “spindle cell sarcoma” or “leptomeningeal melanocytoma” as keywords. The database search was restricted to pediatric patients (age ≤ 18 years). Parameters reported from the literature review included patient age, tumor location, presenting symptoms, treatment modalities (resection, chemotherapy, and/or radiotherapy), leptomeningeal spread at or after the time of treatment, and follow-up length and resulting outcome. RESULTS The authors report 3 rare cases of posterior fossa malignant spindle cell tumors, including Ewing sarcoma in a 13-year-old male; high-grade spindle cell sarcoma, not otherwise specified in a 10-year-old male; and primary leptomeningeal melanocytoma in a 16-year-old female. All 3 patients underwent resection and radiotherapy and either chemotherapy or targeted immunotherapy. At the last follow-up, all patients were alive with either resolution or stable disease. CONCLUSIONS A review of these 3 cases and the existing literature support managing patients with intracranial malignant spindle cell tumors with multimodal therapy that can include a combination of resection, radiotherapy, and chemotherapy or immunotherapy to prolong progression-free and overall survival.

show abstract

Section: High-grade Spindle Cell Sarcoma Nosmentioning

confidence: 99%

Section: High-grade Spindle Cell Sarcoma Nosmentioning

confidence: 99%

Section: High-grade Spindle Cell Sarcoma Nosmentioning

confidence: 99%

Section: High-grade Spindle Cell Sarcoma Nosmentioning

confidence: 99%

See 2 more Smart Citations

Malignant spindle cell tumors of the posterior fossa in children: case series and review of management

Gigliotti

Mau

Specht

et al. 2021

Journal of Neurosurgery: Pediatrics

View full text Add to dashboard Cite

show abstract

“…In the process of teaching the English subject, constraints often arise. Megawati (2016) mentions that the difficulties that inhibit students in using English is their inability to pronounce English words well. This inability can lower their self-confidence in using their oral English in everyday life.…”

Section: Introductionmentioning

confidence: 99%

Blended learning innovation of social media based active English during the COVID-19 pandemic

2021

ilkonline

View full text Add to dashboard Cite

This study aims to describe the implementation of blended learning innovation of social mediabased (sosmed-based) English teaching in improving students' active English skill during the Covid19 Pandemic. The innovation was made by implementing the Communicative Approach which integrated elearning platforms including Be-Smart, Zoom, and Google Classroom with social media (YouTube, Instagram, Facebook). The indicators of active English skill are: students' activeness, self-confidence, and creativity and innovation in producing and uploading the videos of English practice to the social media during English classes. This research used the qualitative approach with the case study type. The subjects were PTE students of classes 2A, B, C, and D, Faculty of Education, Yogyakarta State University in the academic year of 2019-2020. The subjects were one lecturer and eight students established by using the purposive sampling technique. This study was conducted from January to April 2020. The data were collected though observation, interviews, field notes, and documentation. The data analysis used the interactive analysis form Miles and Huberman. The result shows that the innovation of blended learning in sosmed-based active English class which used the Communicative Approach integrated e-learning platforms of Be-Smart, Zoom, and Google Classroom with social media (YouTube, Instagram, Facebook) could improve active English skill of the students in Covid19 pandemic. This can be seen from the students' activeness and self-confidence, creativity and innovation in producing and uploading the videos of English practice because they need a number of likes, views, and subscribers so it could naturally motivate them to do their best in order to improve their motivation and active English skill.

show abstract

MRI findings of primary intracranial sarcomas in children

et al. 2023

View full text Add to dashboard Cite

Epileptic seizure in primary intracranial sarcoma: a case report and literature review

Abstract: Epileptic seizures as one of the clinical manifestations are uncommon. The two most common seizure types were generalized seizures and status epilepticus. The most frequent location of primary intracranial sarcoma-related seizures was the frontal lobe. The clinical outcome varied.

Cited by 4 publications

References 36 publications

Malignant spindle cell tumors of the posterior fossa in children: case series and review of management

Malignant spindle cell tumors of the posterior fossa in children: case series and review of management

Blended learning innovation of social media based active English during the COVID-19 pandemic

MRI findings of primary intracranial sarcomas in children

Contact Info

Product

Resources

About