Epileptic discharges triggered by blinking and eye closure

Vignaendra, Velupillay; Ghee, Thiam; Loh,; Lee, Chong; Lim,; Tin, Siew; Chen, Guihai

doi:10.1016/0013-4694(76)90079-1

Cited by 23 publications

(7 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…No reference could be found of a study of the effect on the EEG of opening and closing the eyes in the dark; there are rare reports of eyeclosure in the dark provoking EEG seizure activity. 30 More investigations might have been undertaken in our patient. The effect of closing one eye at a time was not tested.…”

Section: The Role Of Eye-closurementioning

confidence: 88%

Visual Hallucinations on Eye Closure Associated with Atropine Toxicity. A Neurological Analysis and Comparison with other Visual Hallucinations

Fisher

1991

Can. j. neurol. sci.

View full text Add to dashboard Cite

ABSTRACT:Visual hallucinations of remarkable intensity began shortly after intravenous atropine and persisted for 11 days. They were present only when the eyes were closed and were associated with heightened dreaming and disturbed sleep. The patient remained lucid and described his experiences to his attendants. Our patient's hallucinations bore some resemblance to hypnagogic hallucinations and this became the basis for the hypothesis that the hallucinations originated in the sleep-dream system of the brain stem. It is speculated that a similar site — a metabolic locus minoris resistentiae may play a part in other types of visual hallucinations and in delirium.

show abstract

Section: The Role Of Eye-closurementioning

confidence: 88%

Visual Hallucinations on Eye Closure Associated with Atropine Toxicity. A Neurological Analysis and Comparison with other Visual Hallucinations

Fisher

1991

Can. j. neurol. sci.

View full text Add to dashboard Cite

show abstract

“…They are known to occur in patients with focal occipital seizures and in idiopathic generalized epilepsies such as JME, eyelid myoclonia, JAE and CAE [3]. In the latter group, two different mechanisms were proposed: (a) the physical movement of the eye lids [4], (b) the abrupt blockage of visual sensory input [5,6]. To the best of our knowledge, the ability to block the generation of a paroxysm by mental activity has not been previously reported.…”

Section: Discussionmentioning

confidence: 99%

Blockage of eye-closure-generated generalized paroxysms by mental activity

Amit¹,

Amit

2015

J Pediatr Neurol

View full text Add to dashboard Cite

Seizures and electroencephalography (EEG) paroxysms induced by eye closure. Are rare but a recognized form of stimulus induced epilepsy. We report a case of a 15-year-old male diagnosed with juvenile absence epilepsy in whom EEG paroxysms in the form of generalized three per second spike and wave bursts generated by sustained eye closure were consistently blocked during mental activity in the form of skip counting. To the best of our knowledge, this phenomenon has not been previously reported. We propose two possible mechanisms to account for this blockage, both based on reduction of excitability: (1) blockage of the seizures in the brainstem at the level of the reticular activating system, by raising the level of attention, via the thalamo-cortical circuitry, (2) task-specific, based on the model mechanism of ?winner-takes-all? which generates enhanced inhibition to produce cognitive selectivity.

show abstract

“…On the other hand, some reports have disclosed that eye closure and blinking also provoke spike-wave discharges 7,8 . In our case, these discharges can be recorded even in complete darkness, the discharge may arise from afferent stimuli from the extraocular muscles or orbicularis oculi 9 , or other mechanisms such as activation of the cortex due to the change of consciousness level. Green and his associates suggest an important role of voluntary eye closure in triggering seizure activity by the EEG studies in the photosensitive group.…”

Section: Discussionmentioning

confidence: 89%

The relationship between photosensitive temporal lobe epilepsy and eye closure activity

Inoue

Mimori

Harada

et al. 2000

Seizure

View full text Add to dashboard Cite

We describe a 16-year-old female patient affected by photo-induced temporal lobe epilepsy. During intermittent photic stimulation she showed a photoparoxysmal response in the EEG. This case was diagnosed from clinical symptoms, single photon emission computer tomography, and EEG data. The clinical symptoms were relieved by the administration of carbamazepine. As these photoparoxysmal responses were observed not only during photic stimulation, but also when patient was closing her eyes during an eye-opening test in complete darkness, we propose the existence of an alternative pathway such as from the extraocular muscles or orbicularis oculi, or activation of cortical activity due to the change of consciousness by closing eyes in inducing photosensitive epilepsy. We describe an additional case and discuss a novel aspect of photo-induced temporal lobe epilepsy.

show abstract

Epileptic discharges triggered by blinking and eye closure

Cited by 23 publications

References 8 publications

Visual Hallucinations on Eye Closure Associated with Atropine Toxicity. A Neurological Analysis and Comparison with other Visual Hallucinations

Visual Hallucinations on Eye Closure Associated with Atropine Toxicity. A Neurological Analysis and Comparison with other Visual Hallucinations

Blockage of eye-closure-generated generalized paroxysms by mental activity

The relationship between photosensitive temporal lobe epilepsy and eye closure activity

Contact Info

Product

Resources

About