Epilepsy induced by severe hypoglycemia: about 3 cases

Meryam, Elbahi; Rafi, Sana; Elmghari, G.; Elansari, N.

doi:10.1530/endoabs.63.p1036

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…12 In a study conducted by Tardy et al, it was observed that metabolic abnormalities presented as first episode of seizure and similarly in present study it was found that 6 patients presented with GTCS following hyperglycemia (>300mg/dl), 4 patients following hypoglycemia(<75mg/dl) and 5 patients following hyponatremia (<120mM/l). [13][14][15] Studies have shown that hyperglycemia causes decreased GABA levels secondary to increased metabolism and also reversible focal ischemia secondary to hyperosmolarity causing abnormal neuronal hyperexcitability leading to seizures. 16,17 On the other hand hypoglycemia causes raise in glutamate and aspartate out of proportion to raise in GABA causing excitatory activity in neurons leading to seizures.…”

Section: Discussionmentioning

confidence: 99%

Study of clinical radiological and EEG profile of patients presenting with first episode of generalized tonic clonic convulsions to a tertiary care center

Awati

2022

IJN

View full text Add to dashboard Cite

Generalised Tonic Clonic Convulsions are one of the common presentation to the emergency department. Proper understanding and approach to the same for a practicing doctor and education to the patient and its family helps in avoiding recurrence and the myths associated with it. Not many studies have studied the association of this clinical presentation in relation to neuroimaging and electroencephalography, hence this study. Study was conducted over a period of 2 years where in all patients presenting to the out patient and emergency department with first episode of generalized tonic clonic convulsion were taken into consideration. Necessary investigation were performed especially MRI Brain and EEG, the data was analysed across various variables and corelated. In present study it was noted around 34% of patients had no specific cause, 60% had normal MRI, 40% had abnormal EEG, incidence was higher in males and in patients in age group between 18-45 years. Stroke and alcohol withdrawal were other common causes followed by metabolic abnormalities, cerebral venous thrombosis, posterior reversible encephalopathy syndrome and cns infections. A detailed history regarding semiology has to be collected, even though sometimes it is difficult to obtain the same. In such situations neuroimaging like MRI Brain and Electroencephalography should be performed in every patient presenting with first episode of generalized tonic clonic convulsion. This approach helps in preventing the recurrences and identifying the exact cause and management of the patients.

show abstract

Section: Discussionmentioning

confidence: 99%

Study of clinical radiological and EEG profile of patients presenting with first episode of generalized tonic clonic convulsions to a tertiary care center

Awati

2022

IJN

View full text Add to dashboard Cite

show abstract

Epilepsy induced by severe hypoglycemia: about 3 cases

Cited by 1 publication

References 0 publications

Study of clinical radiological and EEG profile of patients presenting with first episode of generalized tonic clonic convulsions to a tertiary care center

Study of clinical radiological and EEG profile of patients presenting with first episode of generalized tonic clonic convulsions to a tertiary care center

Contact Info

Product

Resources

About