Epilepsy in Sardinia, Insular Italy: A Population-Based Prevalence Study

Cossu, P; Deriu, M.; Casetta, Ilaria; Leoni, Stefania; Daltveit, Anne Kjersti; Riise, Trond; Rosati, Giulio; Pugliatti, Maura

doi:10.1159/000336005

Cited by 14 publications

(16 citation statements)

References 62 publications

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“…Our findings are in keeping with European and North American reports [17,18]. Prevalence ranged from 3.1 to 6.6 per 1,000 in other Italian studies [1,2,3,4,5,19]. The different methods for case ascertainment may explain some differences; our highest prevalence may be also due to the inclusion of subjects in remission or currently untreated but still followed for regular checks.…”

Section: Discussionsupporting

confidence: 89%

“…Published reports on the prevalence and incidence of epilepsy in Italy are few and, with one exception [1], are based on small samples [2,3], treated patients [4,] or children and adolescents [5]. Registries and databases in well-defined populations are useful instruments for the collection of data to be used for epidemiological purposes and to monitor drug prescriptions and drug safety.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence and Incidence of Epilepsy in Italy Based on a Nationwide Database

Giussani

Cricelli²,

Mazzoleni³

et al. 2014

Neuroepidemiology

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Objectives: To estimate the prevalence and incidence of epilepsy in Italy using a national database of general practitioners (GPs). Methods: The Health Search CSD Longitudinal Patient Database (HSD) has been established in 1998 by the Italian College of GPs. Participants were 700 GPs, representing a population of 912,458. For each patient, information on age and sex, EEG, CT scan, and MRI was included. Prevalent cases with a diagnosis of ‘epilepsy' (ICD9CM: 345*) were selected in the 2011 population. Incident cases of epilepsy were identified in 2011 by excluding patients diagnosed for epilepsy and convulsions and those with EEG, CT scan, MRI prescribed for epilepsy and/or convulsions in the previous years. Crude and standardized (Italian population) prevalence and incidence were calculated. Results: Crude prevalence of epilepsy was 7.9 per 1,000 (men 8.1; women 7.7). The highest prevalence was in patients <25 years and ≥75 years. The incidence of epilepsy was 33.5 per 100,000 (women 35.3; men 31.5). The highest incidence was in women <25 years and in men 75 years or older. Conclusions: Prevalence and incidence of epilepsy in this study were similar to those of other industrialized countries. HSD appears as a reliable data source for the surveillance of epilepsy in Italy. i 2014 S. Karger AG, Basel

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Section: Discussionsupporting

confidence: 89%

Section: Introductionmentioning

confidence: 99%

Prevalence and Incidence of Epilepsy in Italy Based on a Nationwide Database

Giussani

Cricelli²,

Mazzoleni³

et al. 2014

Neuroepidemiology

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“…The standardized prevalence of epilepsy was 4.30 per 1,000. Prevalence ranged from 3.13 to 6.62 per 1,000 in other Italian reports . The different methods for case ascertainment and the use of period rather than point prevalence may explain some differences.…”

Section: Discussionmentioning

confidence: 78%

“…However, investigation of multiple sources is time‐consuming, frequently expensive, and depends on the collaboration of doctors, patients, and health care administrators. Published reports on the prevalence and incidence of epilepsy in Italy are therefore few and, with one exception, are based on small samples or selected subgroups of the general population …”

mentioning

confidence: 99%

Prevalence and incidence of epilepsy in a well‐defined population of Northern Italy

et al. 2014

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SUMMARYObjective: To calculate prevalence and incidence of epilepsy using administrative records. Methods: Claim records from the administrative district of Lecco, Northern Italy (population 311,637; 2001 census), collected during the years 2000-2008, were the data source. Patients of all ages were included. Based on previous findings from our group, the most accurate algorithm to detect epilepsy was the combination of electroencephalography (EEG) (ad hoc code) (at least one during the study period) and antiepileptic drugs (AEDs) (ATC code) (taken in 2008). Using this algorithm, the prevalence of epilepsy for the year 2008 was calculated. The reference population for prevalence was the population residing in the study area during the year 2008. Incident epilepsy cases were a subset of prevalent cases among patients not traced in the years 2000 through 2003. Average annual incidence rates were calculated for 2004 through 2008, taking for reference the person-years of exposure in the resident population. We calculated crude, adjusted (using positive and negative predictive values), and standardized (to the Italian and World population) prevalence and incidence. Results: In 2008, 1,504 patients met the inclusion criteria, giving a prevalence of 4.57 per 1,000 (women 4.26; men 4.89). Prevalence tended to rise slightly with age. There were 864 incident cases, giving an average annual incidence of 53.41 per 100,000 (women 50.98; men 55.95). Incidence rates peaked in the elderly. The adjusted prevalence was 4.42 and the adjusted incidence 47.05. Standardized prevalence and incidence were, respectively, 4.30 per 1,000 and 48.35 per 100,000 (Italian population) and 3.79 per 1,000 and 44.74 per 100,000 (World population). Significance: The prevalence of epilepsy in the Lecco district was comparable to other studies, whereas the incidence was among the highest. With adjustments, administrative records are a cost-effective instrument to monitor epilepsy frequency.

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“…Cinsiyete bağlı prevalans farklılıkları belirgin olmamakla beraber bazı çalışmalarda dikkati çekmektedir. [13][14][15][16] Birçok çalışmada, erkeklerde epilepsi görülme sıklığı, kadınlardan 1,1-1,4 kat daha yüksek bulunmuştur. Ülkemizde yapılan bir çalışmada ise, epilepsi prevalansı kadınlarda 4,5/1000, erkeklerde 7/1000 tespit edilmiştir.…”

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Adana İl Merkezinde Epilepsi Prevalansı ve Sosyodemografik Faktörlerle İlişkisi

Balal¹,

Demır

Aslan

et al. 2017

Turkish Journal of Family Medicine and Primary Care

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ÖZET Amaç: Bu çalışmada, Adana il merkezinde epilepsi prevalansı, hastaların demografik verileri ve epilepsi gelişimindeki risk faktörlerinin belirlenmesi amaçlanmıştır. Gereç ve yöntem: Çalışma, toplum temelli kesitsel olarak planlandı ve Adana il merkezi nüfusu üzerinden ''orantılı tabakalı örneklem yöntemi'' kullanılarak hedef nüfus 7052 kişi olarak belirlendi. Toplumun, sosyoekonomik düzeyini yansıtacak şekilde rastgele örneklem yöntemi ile üç mahalle belirlendi. Hazırlanan anket formları bir doktor ve iki anketör tarafından yüz yüze görüşme yöntemi ile dolduruldu. Hedef nüfus olan 7052 kişiye ulaşıldığında çalışma sonlandırıldı. Daha önceden epilepsi tanısı almış olan veya öykü özellikleri ile epilepsi olabilecek olan grup, hazırlanan diğer anket formlarının doldurularak ileri tetkiklerin yapılması için kliniğimize davet edildi. Bulgular: Anket formu doldurulan 7052 kişinin, 3577'si erkek (%50,7), 3475'i (%49,3) kadındı. Taranan nüfus içerisinde 52 kişi epilepsi olarak tanındı ve aktif epilepsi prevalansı %0,7 olarak bulundu. Epilepsi tespit edilen grubun 31'i (%59,6) erkek 21'i (%40,4) ise kadındı. Sosyoekonomik durumu yüksek olan mahallede prevalans %0,3 sosyoekonomik durumu orta düzeyde olan mahallede %0,7 ve sosyoekonomik durumu düşük olan mahallede ise prevalans %1,4 olarak bulundu. Sosyoekonomik düzey düştükçe, epilepsi prevalansında artış saptandı ve bulgular istatiksel olarak anlamlı bulundu (p<0,001). Sonuç: Elde ettiğimiz veriler, daha önce ülkemizde ve dünyada yapılan prevalans çalışmalarını destekler nitelikte bulunmuştur. Sosyoekonomik düzey yükseldikçe prevalansta düşme saptanmıştır. Bu durum, düşük sosyoekonomik düzeye sahip kişilerin yaşam koşulları nedeniyle prenatal dönemde ve çocukluk çağlarında daha az tıbbi bakım almaları, çalışma şartları nedeniyle daha çok travmaya maruz kalmaları ile açıklanabilir. Ülkemizde epilepsi prevalansı ile ilgili yapılan çalışmalar arttıkça, hastalığın gelişimine katkıda bulunan faktörler daha iyi tanınarak toplumda epilepsi farkındalığının artacağı kuşkusuzdur. Anahtar kelimeler: Epilepsi, prevalans, Adana ABSTRACT Objective: In this study, identification of epilepsy prevalence, epilepsy patients' demographical data and epilepsy risk factors in the Adana city centre is aimed. Methods: This is a community-based cross-sectional study, and by using "proportional stratified sampling method", target population of 7052 people was identified with considering Adana city center population. Three districts, reflecting general socioeconomic status, are identified by using random sampling method. One doctor and two pollsters filled survey forms by face to face interviews. When the target population of 7052 people was reached, the study was terminated. Pre-diagnosed epilepsy patients and participants who are more likely to be diagnosed with the epilepsy in the future, because of their history features, are invited to our clinic for further surveys and investigations. Results: Out of 7052 participants who were face to face interviewed, 3577 of them were male (50,7%) and ...

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Epilepsy in Sardinia, Insular Italy: A Population-Based Prevalence Study

Cited by 14 publications

References 62 publications

Prevalence and Incidence of Epilepsy in Italy Based on a Nationwide Database

Prevalence and Incidence of Epilepsy in Italy Based on a Nationwide Database

Prevalence and incidence of epilepsy in a well‐defined population of Northern Italy

Adana İl Merkezinde Epilepsi Prevalansı ve Sosyodemografik Faktörlerle İlişkisi

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