“…Combination therapy including piracetam, levetiracetam, topiramate and zonisamide, may be necessary to control seizures. Carbamazepines, lamotrigine, oxcarbazepine, GABA analogues (gabapentin, vigabatrin and pregabalin), phenytoin, and fosphenytoin should be avoided, as they may exacerbate myoclonus and myoclonic seizures [26,27]. The goal of seizure management is to achieve sufficient seizure control to support function (social interactions, mobility, fall prevention), while balancing the side effects (e.g., excessive sedation).…”