2019
DOI: 10.3390/children6020015
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Epilepsy in Children with Autistic Spectrum Disorder

Abstract: The comorbidity of autistic spectrum disorder (ASD) and epilepsy has been widely discussed but many questions still remain unanswered. The aim of this study was to establish the occurrence of epilepsy among children with ASD to define the type of epileptic seizures and syndromes, the age of onset of epilepsy, EEG abnormalities, the used antiepileptic drugs and the therapeutic responses for seizures and autistic behavior, as well as to find some correlations between epilepsy and gender, etiology and intellectua… Show more

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Cited by 18 publications
(14 citation statements)
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References 48 publications
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“…Therefore, autism is considered as a comorbidity to epilepsy, and epilepsy is considered as a comorbidity to autism. Both may occur together[ 19 ]. Severity of seizure activity varies from grand mal to subtle activities such as rapid eye blinking, zoning out, inattention for prolonged periods; with/without disturbed consciousness or even epileptic encephalopathies.…”
Section: Neurological Disordersmentioning
confidence: 99%
“…Therefore, autism is considered as a comorbidity to epilepsy, and epilepsy is considered as a comorbidity to autism. Both may occur together[ 19 ]. Severity of seizure activity varies from grand mal to subtle activities such as rapid eye blinking, zoning out, inattention for prolonged periods; with/without disturbed consciousness or even epileptic encephalopathies.…”
Section: Neurological Disordersmentioning
confidence: 99%
“…Loussouarn et al [65] emphasized the high prevalence of EEG abnormalities in children with ASD without epilepsy, and that EEG should only be performed at epilepsy onset, and more precisely when a clinical interview has confirmed that repetitive paroxysmal events could be seizures. Pacheva et al [66] postulate that in the occurrence of epilepsy among children with ASD we should define the type of epileptic seizures and syndromes, the age of onset of epilepsy, EEG abnormalities, the used antiepileptic drugs and the therapeutic responses for seizures and autistic behavior, as well as to find some correlations between epilepsy and gender, etiology and intellectual disability (ID).…”
Section: Abnormalities On Electroencephalography (Eeg) Resultsmentioning
confidence: 99%
“…In many works, common pathophysiological mechanisms have been shown to underlie both of these diseases Appearance of both could be determined by structural abnormalities in CNS, genetic and environmental factors, metabolic disorders or perinatal injuries. Key words: epilepsy, autism, ASD, intellectual disability, EEG Zaburzenia ze spektrum autyzmu (autistic spectrum disorders ASD) to coraz częściej rozpoznawane biologiczne zaburzenia neurorozwojowe charakteryzujące się upośledzeniem komunikacji i interakcji społecznych oraz stereotypowością zachowań i zainteresowań, występują u 0,75% do 1,1% populacji [1,2]. Padaczka z różnymi rodzajami napadów pojawia się u około 0,4% do 0,8% populacji [3].…”
Section: Discussionunclassified
“…[6] 2,7%-44,4% Buckley i Holmes [7] 5%-46% Pacheva i wsp. [2] 15,2% Matsuo i wsp. [8] 5%-37% Berg i Plioplys [5] 8,6% Thomas i wsp.…”
Section: 7%mentioning
confidence: 99%