Epilepsy in British Shorthair cats in Sweden

Tenger, Marianne; Meervenne, Sofie Van; Varjonen, Katarina; Tidholm, Anna; Rohdin, Cecilia

doi:10.1177/1098612x211036795

Cited by 3 publications

(3 citation statements)

References 44 publications

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“…Cluster seizures are defined as ≥2 or more seizures within a 24‐hour period 10 . They are common in veterinary medicine with reported incidence of 38% to 77% in dogs and 27% to 43% in cats 11‐14 . Cluster seizures may evolve into status epilepticus with 1 study showing convulsive status epilepticus in 44% of human patients with cluster seizures 15 .…”

Section: Introductionmentioning

confidence: 99%

“… 10 They are common in veterinary medicine with reported incidence of 38% to 77% in dogs and 27% to 43% in cats. 11 , 12 , 13 , 14 Cluster seizures may evolve into status epilepticus with 1 study showing convulsive status epilepticus in 44% of human patients with cluster seizures. 15 This study showed that patients who experience cluster seizures are at a significantly higher risk for convulsive status epilepticus than are patients with nonclustered seizures.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of nonconvulsive seizures and nonconvulsive status epilepticus in dogs and cats with a history of cluster seizures: A retrospective study

Tästensen,

Gutmann,

Loderstedt

et al. 2023

Veterinary Internal Medicne

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BackgroundNonconvulsive seizures (NCS) and nonconvulsive status epilepticus (NCSE) are frequently observed in human patients. Diagnosis of NCS and NCSE only can be achieved by the use of electroencephalography (EEG). Electroencephalographic monitoring is rare in veterinary medicine and consequently there is limited data on frequency of NCS and NCSE.ObjectivesDetermine the prevalence of NCS and NCSE in dogs and cats with a history of cluster seizures.AnimalsTwenty‐six dogs and 12 cats.MethodsRetrospective study. Medical records of dogs and cats with cluster seizures were reviewed. Electroencephalography was performed in order to identify electrographic seizure activity after the apparent cessation of convulsive seizure activity.ResultsNonconvulsive seizures were detected in 9 dogs and 2 cats out of the 38 patients (29%). Nonconvulsive status epilepticus was detected in 4 dogs and 2 cats (16%). Five patients had both NCS and NCSE. A decreased level of consciousness was evident in 6/11 patients with NCS, 3/6 also had NCSE. Mortality rate for patients with NCS (73%) and NCSE (67%) was much higher than that for patients with no seizure activity on EEG (27%).Conclusion and Clinical ImportancePrevalence of NCS and NCSE is high in dogs and cats with a history of cluster seizures. Nonconvulsive seizures and NCSE are difficult to detect clinically and are associated with higher in hospital mortality rates. Results indicate that prompt EEG monitoring should be performed in dogs and cats with cluster seizures.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Prevalence of nonconvulsive seizures and nonconvulsive status epilepticus in dogs and cats with a history of cluster seizures: A retrospective study

Tästensen,

Gutmann,

Loderstedt

et al. 2023

Veterinary Internal Medicne

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“… 1 , 2 Although the terminology for epilepsy classification has been agreed on in dogs, 3 no consensus has been reached for cats. 2 , 4 – 8 Therefore, this paper will use ‘presumptive idiopathic epilepsy’ (PIE) when referring to idiopathic epilepsy in cats. The prevalence of PIE in cats with recurrent epileptic seizures has been reported to be in the range of 22%–75%, 1 , 2 , 7 , 9 – 12 with the majority having seizure onset at 1–5 years.…”

Section: Introductionmentioning

confidence: 99%

Once-a-day oral treatment with phenobarbital in cats with presumptive idiopathic epilepsy

Mojarradi,

De Decker,

Van Meervenne

2023

Journal of Feline Medicine and Surgery

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Objectives Phenobarbital (PB) q12h is the most common treatment recommendation for cats with recurrent epileptic seizures. Medicating cats may be challenging and result in decreased quality of life for both cat and owner. The aim of this retrospective study was to evaluate treatment with oral PB q24h in cats with presumptive idiopathic epilepsy. Methods Nine cats with presumptive idiopathic epilepsy, receiving oral PB q24h, were included in a retrospective descriptive study. Results Seizure remission was achieved in 88% (8/9) of the cats and good seizure control in 12% (1/9) of the cats, treated with a mean dose of oral PB of 2.6 mg/kg q24h (range 1.4–3.8 mg/kg). No cats required an increase of their PB frequency at any time during a mean follow-up period of 3.5 years (range 1.1–8.0 years). No cats displayed side effects or issues with compliance at the last recorded follow-up. Conclusions and relevance Once-a-day administration of PB for feline epilepsy was safe and resulted in satisfactory seizure control for the nine cats included in this study. The results of this study justify exploring this topic further in larger prospective studies.

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Clinical Course and Diagnostic Findings of Biopsy Controlled Presumed Immune-Mediated Polyneuropathy in 70 European Cats

et al. 2022

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There is a paucity of information on the clinical course and outcome of young cats with polyneuropathy. The aim of the study was to describe the clinical features, diagnostic investigations, and outcome of a large cohort of cats with inflammatory polyneuropathy from several European countries. Seventy cats with inflammatory infiltrates in intramuscular nerves and/or peripheral nerve biopsies were retrospectively included. Information from medical records and follow up were acquired via questionnaires filled by veterinary neurologists who had submitted muscle and nerve biopsies (2011–2019). Median age at onset was 10 months (range: 4–120 months). The most common breed was British short hair (25.7%), followed by Domestic short hair (24.3%), Bengal cat (11.4%), Maine Coon (8.6%) and Persian cat (5.7%), and 14 other breeds. Male cats were predominantly affected (64.3%). Clinical signs were weakness (98.6%) and tetraparesis (75.7%) in association with decreased withdrawal reflexes (83.6%) and, less commonly, cranial nerve signs (17.1%), spinal pain/hyperesthesia (12.9%), and micturition/defecation problems (14.3%). Onset was sudden (30.1%) or insidious (69.1%), and an initial progressive phase was reported in 74.3%. Characteristic findings on electrodiagnostic examination were presence of generalized spontaneous electric muscle activity (89.6%), decreased motor nerve conduction velocity (52.3%), abnormal F-wave studies (72.4%), pattern of temporal dispersion (26.1%) and unremarkable sensory tests. The clinical course was mainly described as remittent (49.2%) or remittent-relapsing (34.9%), while stagnation, progressive course or waxing and waning were less frequently reported. Relapses were common and occurred in 35.7% of the cats' population. An overall favorable outcome was reported in 79.4% of patients. In conclusion, young age at the time of diagnosis and sudden onset of clinical signs were significantly associated with recovery (p < 0.05). Clinical and electrodiagnostic features and the remittent-relapsing clinical course resembles juvenile chronic inflammatory demyelinating polyneuropathy (CIDP), as seen in human (children/adolescents), in many aspects.

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Epilepsy in British Shorthair cats in Sweden

Cited by 3 publications

References 44 publications

Prevalence of nonconvulsive seizures and nonconvulsive status epilepticus in dogs and cats with a history of cluster seizures: A retrospective study

Prevalence of nonconvulsive seizures and nonconvulsive status epilepticus in dogs and cats with a history of cluster seizures: A retrospective study

Once-a-day oral treatment with phenobarbital in cats with presumptive idiopathic epilepsy

Clinical Course and Diagnostic Findings of Biopsy Controlled Presumed Immune-Mediated Polyneuropathy in 70 European Cats

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