“…Neuroinhibitory amino acids, such as GABA, glycine and taurine, also have been identified as prominent contributing components in processes associated with seizure phenomena (Van Gelder, 1972;Ribak et al, 1979;Haug and Nitsch, 1982;Huxtable et al, 1983). The fact that physiological studies continue to provide evidence that these amino acids depress the firing rate of central neurons has supported the argument that these sUbstances may function to maintain a homeostatic level of neuronal excitability and under conditions of hyperexcitability serve as endogenous anticonvulsants (Barbeau et al, 1975;Phillis, 1978;Huxtable, 1981;Toth et al, 1983;Lehmann et al, 1984).…”